ID G7NAF3_MACMU Unreviewed; 454 AA.
AC G7NAF3; F6UN59; H9FQU4;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 03-MAY-2023, entry version 68.
DE SubName: Full=Docking protein 1 isoform 1 {ECO:0000313|EMBL:AFE77003.1};
GN Name=DOK1 {ECO:0000313|EMBL:AFE77003.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:AFE77003.1};
RN [1] {ECO:0000313|EMBL:AFE77003.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Caudate {ECO:0000313|EMBL:AFE77003.1}, and Thymus
RC {ECO:0000313|EMBL:AFH31361.1};
RX PubMed=25319552; DOI=10.1186/1745-6150-9-20;
RA Zimin A.V., Cornish A.S., Maudhoo M.D., Gibbs R.M., Zhang X., Pandey S.,
RA Meehan D.T., Wipfler K., Bosinger S.E., Johnson Z.P., Tharp G.K.,
RA Marcais G., Roberts M., Ferguson B., Fox H.S., Treangen T., Salzberg S.L.,
RA Yorke J.A., Norgren R.B.Jr.;
RT "A new rhesus macaque assembly and annotation for next-generation
RT sequencing analyses.";
RL Biol. Direct 9:20-20(2014).
CC -!- SIMILARITY: Belongs to the DOK family. Type A subfamily.
CC {ECO:0000256|ARBA:ARBA00010955}.
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DR EMBL; JU333248; AFE77003.1; -; mRNA.
DR EMBL; JU474557; AFH31361.1; -; mRNA.
DR RefSeq; XP_001111248.3; XM_001111248.3.
DR AlphaFoldDB; G7NAF3; -.
DR GeneID; 710118; -.
DR KEGG; mcc:710118; -.
DR CTD; 1796; -.
DR eggNOG; KOG4047; Eukaryota.
DR HOGENOM; CLU_030101_3_1_1; -.
DR OrthoDB; 2996885at2759; -.
DR CDD; cd01203; PTB_DOK1_DOK2_DOK3; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR InterPro; IPR037751; Dok1/2/3_PTB.
DR InterPro; IPR002404; IRS_PTB.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR21258:SF46; DOCKING PROTEIN 1; 1.
DR PANTHER; PTHR21258; DOCKING PROTEIN RELATED; 1.
DR Pfam; PF02174; IRS; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM01244; IRS; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00310; PTBI; 1.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR PROSITE; PS51064; IRS_PTB; 1.
PE 2: Evidence at transcript level;
FT DOMAIN 151..259
FT /note="IRS-type PTB"
FT /evidence="ECO:0000259|PROSITE:PS51064"
FT REGION 270..293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 307..330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 357..377
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 399..454
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 430..454
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 454 AA; 49678 MW; 4C965305C8FB9208 CRC64;
MDGAVMEGPL FLQSQRFGTK RWRKTWAVLY PASPHGVARL EFFDHKGSSS GGGRGSSRRL
DCKVIRLAEC VSVAPVTVDT PPEPGATAFR LDTAQRSHLL AADAPSSAAW VQTLCRNAFP
KGSWTLAPSD NPPKLSALEM LENSLYSPTW EGSQFWVTVQ RTEAAERCGL HGSYVLRVET
ERLTLLTMGA QSQILEPLLS WPYTLLRRYG RDKVMFSFEA GRRCPSGPGT FTFQTAQGND
IFQAVETAIH RQKAQGKAGQ GHDVLRADSH EGEVAEGKLP SPPGPQELLD SPPALYAEPL
DSLRIAPCPS QDSLYSDPLD STPARAGEGV QRKKPLYWDL FEHAQQQLLK AKLTDPKEDP
IYDEPEGLAP VPPQGLYDLP REPKDAWWCQ ARVKEEGYEL PYNPATDDYA VPPPRSTKPL
PAPKPEPGTA TGSGSKSYNS ALYSQVHKSG ASGS
//
