ID G7NUI7_MACFA Unreviewed; 392 AA.
AC G7NUI7;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 22-FEB-2023, entry version 23.
DE RecName: Full=SH2 domain-containing protein {ECO:0000259|PROSITE:PS50001};
DE Flags: Fragment;
GN ORFNames=EGM_01136 {ECO:0000313|EMBL:EHH50325.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1] {ECO:0000313|EMBL:EHH50325.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CE-4 {ECO:0000313|EMBL:EHH50325.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
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DR EMBL; CM001276; EHH50325.1; -; Genomic_DNA.
DR AlphaFoldDB; G7NUI7; -.
DR eggNOG; ENOG502R9PR; Eukaryota.
DR Proteomes; UP000009130; Chromosome 1.
DR CDD; cd10391; SH2_SHE; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR035042; SHE_SH2.
DR PANTHER; PTHR15127; HEAVYWEIGHT, ISOFORM A; 1.
DR PANTHER; PTHR15127:SF29; SH2 DOMAIN-CONTAINING ADAPTER PROTEIN E; 1.
DR Pfam; PF00017; SH2; 1.
DR PRINTS; PR00401; SH2DOMAIN.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50001; SH2; 1.
PE 4: Predicted;
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT DOMAIN 292..387
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 1..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 100..130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 157..224
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..124
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 198..224
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EHH50325.1"
FT NON_TER 392
FT /evidence="ECO:0000313|EMBL:EHH50325.1"
SQ SEQUENCE 392 AA; 43675 MW; B36B348A86B6B8A8 CRC64;
SRDSLQGLIQ AAAGKGRKNS RATEEEPHRG ATKSSGCSTY INRLIKVDTQ EKNGKSNYPS
SSSSSSSSSS SVSSSPSSLG PELDKSKIIK QQDTVIILED YADPYDAKRT KGQRDAERVG
ENDGYMEPYD AQQMITEIRR RGSKDPLVKA LQLLDSPCEP AEGGLKSETL AKRRSSKDLL
GKPPQLYDTP YEPAEGGPRA EGKARPPDSR LPENDERPAA EYEQPWEWKK EQIVRALSVQ
FEGAERPSVR EETVRQHHRQ KSWTQKILKP ALSDHSEGEK VDPGLPLEKQ PWYHGAISRA
EAESRLQPCK EAGYLVRNSE SGNSRYSIAL KTSQGCVHII VAQTKDNKYT LNQTSAVFDS
IPEVVHYYSN EKLPFKGAEH MTLLYPVHSK LH
//
