ID G7NUP0_MACFA Unreviewed; 1172 AA.
AC G7NUP0;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Laminin subunit beta-3 {ECO:0008006|Google:ProtNLM};
GN ORFNames=EGM_01434 {ECO:0000313|EMBL:EHH50580.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1] {ECO:0000313|EMBL:EHH50580.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CE-4 {ECO:0000313|EMBL:EHH50580.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00460}.
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DR EMBL; CM001276; EHH50580.1; -; Genomic_DNA.
DR AlphaFoldDB; G7NUP0; -.
DR eggNOG; KOG0994; Eukaryota.
DR Proteomes; UP000009130; Chromosome 1.
DR CDD; cd22303; cc_LAMB3_C; 1.
DR CDD; cd00055; EGF_Lam; 6.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 4.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 2.170.300.10; Tie2 ligand-binding domain superfamily; 1.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR008211; Laminin_N.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR10574:SF268; LAMININ SUBUNIT BETA-3; 1.
DR PANTHER; PTHR10574; NETRIN/LAMININ-RELATED; 1.
DR Pfam; PF00053; Laminin_EGF; 6.
DR Pfam; PF00055; Laminin_N; 1.
DR PRINTS; PR00011; EGFLAMININ.
DR SMART; SM00180; EGF_Lam; 6.
DR SMART; SM00136; LamNT; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 5.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01248; EGF_LAM_1; 2.
DR PROSITE; PS50027; EGF_LAM_2; 6.
DR PROSITE; PS51117; LAMININ_NTER; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00460};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..1172
FT /note="Laminin subunit beta-3"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003501242"
FT DOMAIN 22..249
FT /note="Laminin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51117"
FT DOMAIN 250..315
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 316..378
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 379..430
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 431..480
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 481..533
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 534..580
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT REGION 747..766
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 839..873
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 949..979
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1043..1070
FT /evidence="ECO:0000256|SAM:Coils"
FT DISULFID 281..290
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 346..355
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 401..410
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 453..462
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 481..493
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 483..500
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 502..511
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 534..546
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 536..553
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 555..564
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
SQ SEQUENCE 1172 AA; 129456 MW; D8F8E222BE3985CE CRC64;
MRPLFLLCFA LPGLLHAQQA CSRGACYPPV GDLLVGRTRF LRASSTCGLT KPETYCTQHG
EWQMKCCKCD SRQPHNYYSH RVENVASSSG PMRWWQSQND VNPVSLQLDL DRRFQLQEVM
MEFQGPMPAG MLIERSSDFG KTWRVYQYLA ADCTSTFPRV RQGRPQSWQD VRCQSLPQRP
NVRLNGGKVQ LNLMDLASGI PATQSKKIQE LGEITNLRVN FTRLAPVPQR GYHPPSAYYA
VSQLRLQGSC FCHGHADRCA PKPGASAGPS TTMQVHDVCV CQHNTAGPNC ERCAPFYNNR
PWRPAEGRDT HECQRCDCNG HSETCHFDPA VFAASQGAYG GVCDNCRDHT EGKNCERCQL
HYFRNRRPGA SIQETCIPCE CDPDGAVPGA PCDPVTGQCV CKEHVQGERC DLCKPGFTGL
TYANPQGCHR CDCNILGSRR DVPCDEESGR CLCLPNVVGP KCDQCAPYHW KLASGQGCEP
CACDPHNSLS PQCNQFTGQC PCREGFGGLT CSAAAIRQCP DRTYGDAATG CRACDCDFRG
TEGPGCDKAS GRCLCRAGLT GPRCDQCQRG YCNRYPVCVA CHPCFQTYDA DLREQALRLG
SLRNATASLW SGPGLEDRGL ASWILDAKSK IEQIRAVLSS AAVTEQEVAQ VASAILSLRR
ALQGLQPDLP LEEETLSLLR DLESLDRSFN GLLTMYQRKR EQFEKLSSAD PSGAFRMLTT
AYEQSAQAAQ QVSDSSHLLD QLRDSRREAE RLAQQAGGGG GTGSPQLVAL RLEMSSLPDL
TPTFNKLCGS SRQMACTPGS CPGELCPHDN GTACGSHCRG VLPRAGGAFW TAGQVAEQLR
GFNAQLQQTR QMIRAAEESA SQIQSNAQRL ETQVSTSRSQ MEEDVRRTRL LIQQVRDFLT
DPETDAATIQ EVSEAVLALW LPTDSATVLQ KMNEIQAIAA RLPNVDLVLS QTKQDIARAR
RLQAEAEEAR SRAHAVEGQV EDVVGNLRQG TVALQEAQDT MQGTSRSLRL IQDRVAEVQQ
VLQPAEKLVT SMTKQLGDFW TRMEELRRQA RQQRAQAVQA QQLAEGASEQ ALSAQEGFER
IKQKYAELKD RLGQSPTLGE QGAQIQSVKT EAEELFGETM EMMDRMKDME LELLRGSQAI
MLRSADLTGL EKRVEQIRDH INERVLYYAT CK
//
