ID G7NXZ2_MACFA Unreviewed; 404 AA.
AC G7NXZ2;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 24-JAN-2024, entry version 53.
DE SubName: Full=Beaded filament structural protein 2 {ECO:0000313|Ensembl:ENSMFAP00000038073.2};
GN Name=BFSP2 {ECO:0000313|Ensembl:ENSMFAP00000038073.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000038073.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000038073.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000038073.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; G7NXZ2; -.
DR STRING; 9541.ENSMFAP00000038066; -.
DR Ensembl; ENSMFAT00000012326.2; ENSMFAP00000038073.2; ENSMFAG00000038407.2.
DR VEuPathDB; HostDB:ENSMFAG00000038407; -.
DR eggNOG; ENOG502QTD1; Eukaryota.
DR GeneTree; ENSGT00940000159820; -.
DR OrthoDB; 4223979at2759; -.
DR Proteomes; UP000233100; Chromosome 2.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005212; F:structural constituent of eye lens; IEA:Ensembl.
DR GO; GO:0048469; P:cell maturation; IEA:Ensembl.
DR GO; GO:0045109; P:intermediate filament organization; IEA:Ensembl.
DR GO; GO:0070307; P:lens fiber cell development; IEA:Ensembl.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR002957; Keratin_I.
DR PANTHER; PTHR23239; INTERMEDIATE FILAMENT; 1.
DR PANTHER; PTHR23239:SF32; PHAKININ; 1.
DR Pfam; PF00038; Filament; 2.
DR PRINTS; PR01248; TYPE1KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754};
KW Reference proteome {ECO:0000313|Proteomes:UP000233100}.
FT DOMAIN 104..404
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 1..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 199..247
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 303..383
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 14..45
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 404 AA; 44585 MW; 62A5CD14F3CC81ED CRC64;
MSERRVVVDL PPSASSSMPL QRRRASFRGP RSSSSLDSPP ASRTNAMSGL VRAPGVYVGT
APSGCIGGLG ARVTRRALGI SSVFLQGLRS SGLATVPAPG LERDHGAVED LGGCLVEYMA
KVHALEQVSQ ELETQLRMHL ESKATRSGNW GALRASWASS CQQVGEAVLE NARLMLQTET
IQAGADDFKE RYENELPFRK AAEEEINSLY KVIDEANLTK MDLESQIESL KEELGSLSRN
YEEVGRKGLG LLGWPQDQKC TSMIRIQWER DVEKNRVEAG ALLQAKQQAE VAHMSQTQEE
KLAAALRVEL HNTSCQVQSL QAETESLRAL KRGLENTLHD AKHWHDMELQ NLGAVVGRLE
AELSEIRAEA EQQQQERAHL LARKCQLQKD VASYHALLDR EESG
//
