ID G7NYM0_MACFA Unreviewed; 382 AA.
AC G7NYM0;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 24-JAN-2024, entry version 46.
DE SubName: Full=Fetuin B {ECO:0000313|Ensembl:ENSMFAP00000028553.2};
GN Name=FETUB {ECO:0000313|Ensembl:ENSMFAP00000028553.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000028553.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000028553.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000028553.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; G7NYM0; -.
DR STRING; 9541.ENSMFAP00000028553; -.
DR Ensembl; ENSMFAT00000002743.2; ENSMFAP00000028553.2; ENSMFAG00000045631.2.
DR VEuPathDB; HostDB:ENSMFAG00000045631; -.
DR eggNOG; ENOG502S28K; Eukaryota.
DR GeneTree; ENSGT00950000182930; -.
DR OrthoDB; 5351668at2759; -.
DR Proteomes; UP000233100; Chromosome 2.
DR Bgee; ENSMFAG00000045631; Expressed in liver and 1 other cell type or tissue.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:InterPro.
DR GO; GO:0008191; F:metalloendopeptidase inhibitor activity; IEA:Ensembl.
DR GO; GO:0007339; P:binding of sperm to zona pellucida; IEA:Ensembl.
DR CDD; cd00042; CY; 2.
DR Gene3D; 3.10.450.10; -; 2.
DR InterPro; IPR000010; Cystatin_dom.
DR InterPro; IPR025764; Cystatin_Fetuin_B.
DR InterPro; IPR046350; Cystatin_sf.
DR InterPro; IPR001363; Prot_inh_fetuin_CS.
DR PANTHER; PTHR13814; FETUIN; 1.
DR PANTHER; PTHR13814:SF10; FETUIN-B; 1.
DR Pfam; PF00031; Cystatin; 2.
DR SMART; SM00043; CY; 2.
DR SUPFAM; SSF54403; Cystatin/monellin; 2.
DR PROSITE; PS51530; CYSTATIN_FETUIN_B; 2.
DR PROSITE; PS01254; FETUIN_1; 1.
DR PROSITE; PS01255; FETUIN_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..382
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014303921"
FT DOMAIN 25..138
FT /note="Cystatin fetuin-B-type"
FT /evidence="ECO:0000259|PROSITE:PS51530"
FT DOMAIN 149..255
FT /note="Cystatin fetuin-B-type"
FT /evidence="ECO:0000259|PROSITE:PS51530"
FT REGION 281..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 363..382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 281..299
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 382 AA; 42104 MW; 60A36D26D0291B3E CRC64;
MGLPLRLALC TLILCCGARS PPLPVLNPWA LLSRGCNDSD VLAVADFALR DINKDRKDGY
VLSLNRVNDA QEHRQDDLGS LFYLTLDVLE TDCHVLSKKA WRDCGMTPFY QSVYGQCKAI
FYNNKPSRVL YLAAYNCTLR PVSKPKIHRT CPDCPAPTST DLSSDEVLEA ATESLAKYNN
ESTSKQYSLF KVTRASSQWV VGPSYFVEYL IKESPCTKSQ ISSCSLQSSD SVPVGLCKGS
LIRKPWEKLV SVTCDFFESQ APATGSENSA VNQKPINLSK VEESQQKNTA PTDSPSKAGP
RGSVQYLPDL DDNNSQEKDP QEAFPVHLDL TTNPQGETLD LSFLFLEPME KKVVVLPFPR
EKARTAECPG PAQDASPLVL PP
//
