ID G7P4Q8_MACFA Unreviewed; 349 AA.
AC G7P4Q8; I7GEU3;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=FKBP prolyl isomerase like {ECO:0000313|Ensembl:ENSMFAP00000010227.2};
DE SubName: Full=Macaca fascicularis brain cDNA clone: QtrA-17116, similar to human FK506 binding protein like (FKBPL), mRNA, RefSeq: NM_022110.3 {ECO:0000313|EMBL:BAE91519.1};
GN Name=FKBPL {ECO:0000313|Ensembl:ENSMFAP00000010227.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000010227.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|EMBL:BAE91519.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=17194215; DOI=10.1371/journal.pbio.0050013;
RA Wang H.-Y., Chien H.-C., Osada N., Hashimoto K., Sugano S., Gojobori T.,
RA Chou C.-K., Tsai S.-F., Wu C.-I., Shen C.-K.J.;
RT "Rate of evolution in brain-expressed genes in humans and other primates.";
RL PLoS Biol. 5:e13-e13(2007).
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000010227.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSMFAP00000010227.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB174457; BAE91519.1; -; mRNA.
DR RefSeq; NP_001272153.1; NM_001285224.1.
DR RefSeq; XP_005553483.1; XM_005553426.2.
DR SMR; G7P4Q8; -.
DR STRING; 9541.ENSMFAP00000010227; -.
DR Ensembl; ENSMFAT00000039637.2; ENSMFAP00000010227.2; ENSMFAG00000006509.2.
DR GeneID; 101864936; -.
DR KEGG; mcf:101864936; -.
DR CTD; 63943; -.
DR VEuPathDB; HostDB:ENSMFAG00000006509; -.
DR eggNOG; KOG1124; Eukaryota.
DR GeneTree; ENSGT00920000149187; -.
DR OrthoDB; 2939667at2759; -.
DR Proteomes; UP000233100; Chromosome 4.
DR Bgee; ENSMFAG00000006509; Expressed in skeletal muscle tissue and 13 other cell types or tissues.
DR GO; GO:0005576; C:extracellular region; IEA:Ensembl.
DR GO; GO:1905553; P:regulation of blood vessel branching; IEA:Ensembl.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR46423; RNA POLYMERASE II-ASSOCIATED PROTEIN 3; 1.
DR PANTHER; PTHR46423:SF1; RNA POLYMERASE II-ASSOCIATED PROTEIN 3; 1.
DR Pfam; PF00515; TPR_1; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF54534; FKBP-like; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 286..319
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..41
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 349 AA; 38059 MW; FCBCFEEEC0B0B3DE CRC64;
METPAVSTTG EKDTSQPQQQ WEKNLRENFD SVTQIRQQPR DPPTETLELG VSPDPASQIL
ENTQGTEKLV AELEGDSHKS HGSTSQMSEA LQASDLWYCP DGSFVKKIII RGHGLDKPKL
GSCCRVLALG FPFGSGPPEG WTELTMGVGP WREETWGELI EKCLESMCQG EEAELQLPGH
SGPPVRLTLA SFTQGRDSWE LETSEKEALA REERARGTEL FRAGNAEGAA RCYGRALRLL
LTLPPPGPPE RTVLHANLAA CQLLLGQPQL AAQSCDRVLE REPGHLKALY RRGVAQAALG
NLEKATADLK KVLAIDPKNR AAQEELGKVV IQGKKQDAGL AQGLRKMFG
//
