ID G7P856_MACFA Unreviewed; 432 AA.
AC G7P856; A0A2K5VK42;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=GRAM domain containing 2B {ECO:0000313|Ensembl:ENSMFAP00000025110.1};
GN Name=GRAMD2B {ECO:0000313|Ensembl:ENSMFAP00000025110.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000025110.1, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000025110.1, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000025110.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_005557707.1; XM_005557650.2.
DR AlphaFoldDB; G7P856; -.
DR Ensembl; ENSMFAT00000033257.2; ENSMFAP00000025110.1; ENSMFAG00000044063.2.
DR GeneID; 101867113; -.
DR CTD; 65983; -.
DR VEuPathDB; HostDB:ENSMFAG00000044063; -.
DR eggNOG; KOG1032; Eukaryota.
DR GeneTree; ENSGT00940000156980; -.
DR OMA; CKDSRGN; -.
DR OrthoDB; 45896at2759; -.
DR Proteomes; UP000233100; Chromosome 6.
DR Bgee; ENSMFAG00000044063; Expressed in heart and 13 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd13220; PH-GRAM_GRAMDC; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR004182; GRAM.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR46645:SF2; GRAM DOMAIN-CONTAINING PROTEIN 2B; 1.
DR PANTHER; PTHR46645; GRAM DOMAIN-CONTAINING PROTEIN 2B-RELATED; 1.
DR Pfam; PF02893; GRAM; 1.
DR SMART; SM00568; GRAM; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 342..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 220..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 262..284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..43
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 81..101
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 220..237
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 263..284
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 432 AA; 47696 MW; F4CD600C1AACB5E6 CRC64;
MTELQQDVED TKPAKVLGKR ESKVGSAHSE AENGVEEKKK ACRSPTAQSP TPSVEADSPD
QKKIISLRSK SSFDGASLAS DKNDCKTESK NDPKTERKKS SSSGQYKANM HFHKLFLSVP
TEEPLKQSFT CALQKEILYQ GKLFVSENWI CFHSKVFGKD TKISIPAFSV TLIKKTKTAL
LVPNALIIAT VTDRYIFVSL LSRDSTYKLL KSVCGHLENT SVGNSPNPSS AENSFRADRP
SSLPLDFNDE FSDLDGVVQQ RRQDMEGYSS SGSQTPESEN SRDFHVTESQ TVLNVSKGEA
KPTRADAHVN RVPEGKAKSL PAQGLSETVG ILHKVKSQKC PMLHHILIFY AIVVCALIIS
TFYMRYRINT LEEQLGLLTS IVDTHNTEQA APSGLGSQVQ FNVEVLCQEL TANIVKLEKI
QNNLQKLLEN GD
//
