ID   G7PAS3_MACFA            Unreviewed;      1804 AA.
AC   G7PAS3; A0A2K5WLA2;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   SubName: Full=Signal induced proliferation associated 1 like 1 {ECO:0000313|Ensembl:ENSMFAP00000037941.1};
GN   Name=SIPA1L1 {ECO:0000313|Ensembl:ENSMFAP00000037941.1};
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000037941.1, ECO:0000313|Proteomes:UP000233100};
RN   [1] {ECO:0000313|Ensembl:ENSMFAP00000037941.1, ECO:0000313|Proteomes:UP000233100}
RP   NUCLEOTIDE SEQUENCE.
RA   Warren W., Wilson R.K.;
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSMFAP00000037941.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_005561730.1; XM_005561673.2.
DR   RefSeq; XP_005561731.1; XM_005561674.2.
DR   RefSeq; XP_005561732.1; XM_005561675.2.
DR   RefSeq; XP_005561733.1; XM_005561676.2.
DR   RefSeq; XP_005561734.1; XM_005561677.2.
DR   RefSeq; XP_015309443.1; XM_015453957.1.
DR   RefSeq; XP_015309444.1; XM_015453958.1.
DR   RefSeq; XP_015309445.1; XM_015453959.1.
DR   RefSeq; XP_015309446.1; XM_015453960.1.
DR   RefSeq; XP_015309447.1; XM_015453961.1.
DR   RefSeq; XP_015309448.1; XM_015453962.1.
DR   RefSeq; XP_015309449.1; XM_015453963.1.
DR   RefSeq; XP_015309450.1; XM_015453964.1.
DR   RefSeq; XP_015309451.1; XM_015453965.1.
DR   RefSeq; XP_015309452.1; XM_015453966.1.
DR   SMR; G7PAS3; -.
DR   STRING; 9541.ENSMFAP00000037941; -.
DR   Ensembl; ENSMFAT00000012192.2; ENSMFAP00000037941.1; ENSMFAG00000038037.2.
DR   GeneID; 102127679; -.
DR   KEGG; mcf:102127679; -.
DR   CTD; 26037; -.
DR   VEuPathDB; HostDB:ENSMFAG00000038037; -.
DR   eggNOG; KOG3686; Eukaryota.
DR   GeneTree; ENSGT00940000155944; -.
DR   OrthoDB; 25782at2759; -.
DR   Proteomes; UP000233100; Chromosome 7.
DR   Bgee; ENSMFAG00000038037; Expressed in temporal lobe and 13 other cell types or tissues.
DR   GO; GO:0015629; C:actin cytoskeleton; IEA:Ensembl.
DR   GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR   GO; GO:0046875; F:ephrin receptor binding; IEA:Ensembl.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0048013; P:ephrin receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0050770; P:regulation of axonogenesis; IEA:Ensembl.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR   CDD; cd00992; PDZ_signaling; 1.
DR   Gene3D; 2.30.42.10; -; 1.
DR   Gene3D; 6.10.140.210; -; 1.
DR   Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR035974; Rap/Ran-GAP_sf.
DR   InterPro; IPR000331; Rap/Ran_GAP_dom.
DR   InterPro; IPR021818; SIPA1L_C.
DR   PANTHER; PTHR15711; RAP GTPASE-ACTIVATING PROTEIN; 1.
DR   PANTHER; PTHR15711:SF10; SIGNAL-INDUCED PROLIFERATION-ASSOCIATED 1-LIKE PROTEIN 1; 1.
DR   Pfam; PF00595; PDZ; 1.
DR   Pfam; PF21022; Rap-GAP_dimer; 1.
DR   Pfam; PF02145; Rap_GAP; 1.
DR   Pfam; PF11881; SPAR_C; 1.
DR   SMART; SM00228; PDZ; 1.
DR   SUPFAM; SSF50156; PDZ domain-like; 1.
DR   SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR   PROSITE; PS50106; PDZ; 1.
DR   PROSITE; PS50085; RAPGAP; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000233100}.
SQ   SEQUENCE   1804 AA;  200034 MW;  C66787934DEAC470 CRC64;
     MTSLKRSQTE RPLATDRASV VGTDGTPKVH TDDFYMRRFR SQNGSLGSSV MAPVGPPRSE
     GSHHITSTPG VPKMGVRARI ADWPPRKENI KESSRSSQEI ETSSCLDSLS SKSSPVSQGS
     SVSLNSNDSA MLKSIQNTLK NKTRPSENMD SRFLMPEAYP SSPRKALRRI RQRSNSDITI
     SELDVDSFDE CISPTYKTGP SLHREYGSTS SIDKQGTSGE SFFDLLKGYK DDKSDRGPTP
     TKLSDFLITG GSKGSGFSLD VIDGPISQRE NLRLFKEREK PLKRRSKSET GDSSIFRKLR
     NAKGEELGKS SDLEDNRSED SVRPWTCPKC FAHYDVQSIL FDLNEAIMNR HNVIKRRNTT
     TGASAAAVAS LVSGPLSHSA SFSSPMGSTE DLNSKGSLSM DQGDDKSNEL VMSCPYFRNE
     IGGEGERKIS LSKSNSGSFS GCESASFEST LSSHCTNAGV AVLEVPKENL VLHLDRVKRY
     IVEHVDLGAY YYRKFFYQKE HWNYFGADEN LGPVAVSIRR EKPDEMKENG SPYNYRIIFR
     TSELMTLRGS VLEDAIPSTA KHSTARGLPL KEVLEHVVPE LNVQCLRLAF NTPKVTEQLM
     KLDEQGLNYQ QKVGIMYCKA GQSTEEEMYN NESAGPAFEE FLQLLGERVR LKGFEKYRAQ
     LDTKTDSTGT HSLYTTYKDY EIMFHVSTML PYTPNNKQQL LRKRHIGNDI VTIVFQEPGA
     QPFSPKNIRS HFQHVFVIVR VHNPCSDSVC YSVAVTRSRD VPSFGPPIPK GVTFPKSNVF
     RDFLLAKVIN AENAAHKSEK FRAMATRTRQ EYLKDLAEKN VTNTPIDPSG KFPFISLASK
     KKEKSKPYPG AELSSMGAIV WAVRAEDYNK AMELDCLLGI SNEFIVLIEQ ETKSVVFNCS
     CRDVIGWTST DTSLKIFYER GECVSVGSFI NNEEIKEIVK RLQFVSKGCE SVEMTLRRNG
     LGQLGFHVNY EGIVADVEPY GYAWQAGLRQ GSRLVEICKV AVATLSHEQM IDLLRTSVTV
     KVVIIPPHDD CTPRRSCSET YRMPVMEYKM NEGVSYEFKF PFRNNNKWQR NTSKGPHSPQ
     VPSQMQSPMT SRLNAGKGDG KMPPPERAAN IPRSISSDGR PLERRLSPGS DIYVTVSSMA
     LARSQCRNSP SNLSSSSDTG SVGGTYRQKS MPEGFGVSRR SPASIDRQNT QSDIGGSGKS
     TPSWQRSEDS IADQMAYSYR GPQDFNSFVL EQHEYTEPTC HLPAVSKVLP AFRESPSGRL
     MRQDPVVHLS PNKQGHSDSH YSSHSSSNTL SSNASSAHSD EKWYDGDRTE SELNSYNYLQ
     GTSADSGIDT TSYGPSHGST ASLGAATSSP RSGPGKEKVA PLWHSSSEVI SMADRTLETE
     SHGLDRKAES SLSLDIHSKS QAGSSPLTRE NSTFSINDAA SHTSTMSSRH SASPVVFTSA
     RSSPKEELHP AAPSQLAPSF SSSSSSSSGP RSFYPRQGAT SKYLIGWKKP EGTINSVGFM
     DTRKRHQSDG NEIAHTRLRA STRDLRASPK PTSKSTIEED LKKLIDLESP TPESQKSFKF
     HALSSPQSPF PSTPTSRRAL HRTLSDESIY SSQREHFFTS RASLLDQALP NDVLFSSTYP
     SLPKSLPLRR PSYTLGMKSL HGEFSASDSS LTDIQETRRQ PMPDPGLMPL PDTAADLDWS
     NLVDAAKAYE VQRASFFAAS DENHRPLSAA SNSDQLEDQA LAQMKPFSSS KDSSPTLASK
     VDQLEGMLKM LREDLKKEKE DKAHLQAEVQ HLREDNLRLQ EESQNASDKL KKFTEWVFNT
     IDMS
//