ID G7PD96_MACFA Unreviewed; 1047 AA.
AC G7PD96;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=5-oxoprolinase {ECO:0000313|EMBL:EHH64484.1};
GN ORFNames=EGM_17707 {ECO:0000313|EMBL:EHH64484.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1] {ECO:0000313|EMBL:EHH64484.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CE-4 {ECO:0000313|EMBL:EHH64484.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
CC -!- SIMILARITY: Belongs to the oxoprolinase family.
CC {ECO:0000256|ARBA:ARBA00010403}.
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DR EMBL; CM001283; EHH64484.1; -; Genomic_DNA.
DR eggNOG; KOG1939; Eukaryota.
DR Proteomes; UP000009130; Chromosome 8.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR InterPro; IPR049517; ACX-like_C.
DR InterPro; IPR008040; Hydant_A_N.
DR InterPro; IPR002821; Hydantoinase_A.
DR InterPro; IPR003692; Hydantoinase_B.
DR InterPro; IPR045079; Oxoprolinase_fam.
DR PANTHER; PTHR11365:SF2; 5-OXOPROLINASE; 1.
DR PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR Pfam; PF19278; Hydant_A_C; 1.
DR Pfam; PF05378; Hydant_A_N; 1.
DR Pfam; PF01968; Hydantoinase_A; 1.
DR Pfam; PF02538; Hydantoinase_B; 1.
PE 3: Inferred from homology;
FT DOMAIN 10..210
FT /note="Hydantoinase/oxoprolinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF05378"
FT DOMAIN 300..508
FT /note="Hydantoinase A/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF01968"
FT DOMAIN 523..688
FT /note="Acetophenone carboxylase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19278"
FT DOMAIN 712..1030
FT /note="Hydantoinase B/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF02538"
SQ SEQUENCE 1047 AA; 113105 MW; 083F218C8FF5677C CRC64;
MGSPEGRFHF AIDRGGTFTD VFAQCPGGQV RVLKLLSEDP ANYADAPTEG IRRILEQEAG
MLLPRDRPLD SSHIASIRMG TTVATNALLE RKGERVALLV TRGFRDLLHI GTQARGDLFD
LVPMPEVLYE EVLEVDERVV LHRGEAGTGT PVKGRTGDLL DVQQPVDLGT LRGKLEGLLS
RGIRSLAVVL MHSYTWAQHE QQVGALAREL GFSHVSLSSE AMPMVRIVPR GHTACADAYL
TPAIQRYVQG FRRGFQGQLK DVQVLFMRXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXG
TSTDVSRYAG EFEHVFEATT AGVTLQAPQL DINTVAAGGG SRLFFRVGPE SAGAHPGPAC
YRKGGPVTVT DANLVLGRLL PASFPCIFGP GEDQPLSPEA SRKALEAVAT EVNSFLTNGP
CPASPLSLEE VAMGFVRVAN EAMCRPIRAL TQARGHDPSA HVLACFGGAG GQHACAIARA
LGMDTVHIHR HSGLLSALGL ALADVVHEAQ EPCSLLYAPE TFMQLDQRLS RLEEQCVDAL
QAQGFPRSQI STESFLHLRY RGTDCALMVS AHQHPATARS PRAGDFGAAF VERYMREFGF
VIPERPVVVD DVRVRGTGRS GLRLEDAPKA QTGPPRVDKM TQCYFEGGYQ ETPVYLLGEL
GYGHKLHGPC LIIDSNSTIL VEPGCQAEVT ETGDIRISVG AEVPGTMGTQ LDPIQLSIFS
HRFMSIAEQM GRILQRTAIS TNIKERLDFS CALFGPDGGL VSNAPHIPVH LGAMQETVQF
QIQHLGADLH PGDVLLSNHP SAGGSHLPDL TVITPVFWPG QTRPVFYVAS RGHHADIGGI
TPGSMPPHST TLQQEGAVFL SFKLVQGGVF QEEAVTEALR APGKVPNCSG TRNLHDNLSD
LRAQVAANQK GIQLVGELIG QYGLDVVQAY MGHIQANAEL AVRDMLRAFG TSRQARGLPL
EVSSEDHMDD GSPIRLRVQI NLSQGSAVFD FSGTGPEVFG NLNAPRAITL SALIYCLRCL
VGRDIPLNQA FPEHGSVYEY RRAQEAV
//
