ID G7PDT0_MACFA Unreviewed; 569 AA.
AC G7PDT0;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Beta-transducin repeat containing E3 ubiquitin protein ligase {ECO:0000313|Ensembl:ENSMFAP00000010380.2};
GN Name=BTRC {ECO:0000313|Ensembl:ENSMFAP00000010380.2};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000010380.2, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000010380.2, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000010380.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_005566296.1; XM_005566239.2.
DR AlphaFoldDB; G7PDT0; -.
DR SMR; G7PDT0; -.
DR STRING; 9541.ENSMFAP00000010380; -.
DR Ensembl; ENSMFAT00000040340.2; ENSMFAP00000010380.2; ENSMFAG00000005295.2.
DR GeneID; 102136827; -.
DR CTD; 8945; -.
DR VEuPathDB; HostDB:ENSMFAG00000005295; -.
DR eggNOG; KOG0281; Eukaryota.
DR GeneTree; ENSGT00940000159672; -.
DR OrthoDB; 337075at2759; -.
DR Proteomes; UP000233100; Chromosome 9.
DR Bgee; ENSMFAG00000005295; Expressed in temporal lobe and 13 other cell types or tissues.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd22182; F-box_FBXW1A; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.20.1280.50; -; 1.
DR Gene3D; 6.10.250.1840; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR021977; Beta-TrCP_D.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR14604:SF5; F-BOX_WD REPEAT-CONTAINING PROTEIN 1A; 1.
DR PANTHER; PTHR14604; WD40 REPEAT PF20; 1.
DR Pfam; PF12125; Beta-TrCP_D; 1.
DR Pfam; PF12937; F-box-like; 1.
DR Pfam; PF00400; WD40; 7.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM01028; Beta-TrCP_D; 1.
DR SMART; SM00256; FBOX; 1.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF81383; F-box domain; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50181; FBOX; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 5.
DR PROSITE; PS50082; WD_REPEATS_2; 7.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 154..192
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
FT REPEAT 276..293
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 303..342
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 343..382
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 386..425
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 426..465
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 466..497
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 515..554
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ SEQUENCE 569 AA; 65049 MW; 6E7C4FBE7BB520BA CRC64;
MDPAEAVLQE KALKFMNSSE REDCNNGEPP RKIIPEKNSL RQTYNSCARL CLNQETVCLA
STAMKTENCV AKTKLANGTS SMIVPKQRKL SASYEKEKEL CVKYFEQWSE SDQVEFVEHL
ISQMCHYQHG HINSYLKPML QRDFITALPA RGLDHIAENI LSYLDAKSLC AAELVCKEWY
RVTSDGMLWK KLIERMVRTD SLWRGLAERR GWGQYLFKNK PPDGNAPPNS FYRALYPKII
QDIETIESNW RCGRHSLQRI HCRSETSKGV YCLQYDDQKI VSGLRDNTIK IWDKNTLECK
RILTGHTGSV LCLQYDERVI ITGSSDSTVR VWDVNTGEML NTLIHHCEAV LHLRFNNGMM
VTCSKDRSIA VWDMASPTDI TLRRVLVGHR AAVNVVDFDD KYIVSASGDR TIKVWNTSTC
EFVRTLNGHK RGIACLQYRD RLVVSGSSDN TIRLWDIECG ACLRVLEGHE ELVRCIRFDN
KRIVSGAYDG KIKVWDLVAA LDPRAPAGTL CLRTLVEHSG RVFRLQFDEF QIVSSSHDDT
ILIWDFLNDP AAQAEPPRSP SRTYTYISR
//
