ID   G7PGZ6_MACFA            Unreviewed;       351 AA.
AC   G7PGZ6;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   24-JAN-2024, entry version 47.
DE   RecName: Full=Peptidase M24 domain-containing protein {ECO:0000259|Pfam:PF00557};
GN   ORFNames=EGM_02333 {ECO:0000313|EMBL:EHH65552.1};
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1] {ECO:0000313|EMBL:EHH65552.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CE-4 {ECO:0000313|EMBL:EHH65552.1};
RX   PubMed=22002653; DOI=10.1038/nbt.1992;
RA   Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA   Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA   Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA   Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA   Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA   Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT   "Genome sequencing and comparison of two nonhuman primate animal models,
RT   the cynomolgus and Chinese rhesus macaques.";
RL   Nat. Biotechnol. 29:1019-1023(2011).
CC   -!- SIMILARITY: Belongs to the peptidase M24 family.
CC       {ECO:0000256|ARBA:ARBA00007319}.
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DR   EMBL; CM001285; EHH65552.1; -; Genomic_DNA.
DR   AlphaFoldDB; G7PGZ6; -.
DR   Proteomes; UP000009130; Chromosome 10.
DR   CDD; cd01089; PA2G4-like; 1.
DR   Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 2.
DR   InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR   InterPro; IPR004545; PA2G4.
DR   InterPro; IPR047113; PA2G4/ARX1.
DR   InterPro; IPR000994; Pept_M24.
DR   InterPro; IPR018349; Pept_M24A_MAP2_BS.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   NCBIfam; TIGR00495; crvDNA_42K; 1.
DR   PANTHER; PTHR10804:SF11; PROLIFERATION-ASSOCIATED PROTEIN 2G4; 1.
DR   PANTHER; PTHR10804; PROTEASE FAMILY M24 METHIONYL AMINOPEPTIDASE, AMINOPEPTIDASE P; 1.
DR   Pfam; PF00557; Peptidase_M24; 1.
DR   SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS01202; MAP_2; 1.
PE   3: Inferred from homology;
FT   DOMAIN          23..164
FT                   /note="Peptidase M24"
FT                   /evidence="ECO:0000259|Pfam:PF00557"
FT   REGION          321..351
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        330..345
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   351 AA;  39393 MW;  4953A5B7E925F5F4 CRC64;
     MAKDLVVTKY KMGGEGAARC DMANWVLRTL VEASSSGVSV LSLCEKGHAM ITEETEKIFK
     KEKEMNKCIA FPTSISVNNF VCHFFPLKSS QDYILKEGDL VKIDIGFHVD GLIANVAHTC
     VVDLAQGTQV TGRKADVIKI AHLCAEAALC LAKPRNQNTQ VTDVEQKGMQ LKQHVINGEK
     NIIQNPTDQQ KKDQEKAEFE VREVYAVDVL VSLGEGKYEL KMKTSRAFFS EVERCFDAMP
     FTLRAFEDEK KAWMGVVECT KHGLLQPFNV LSEKEGEFVA QFKFAILLMP NGPMQITSGP
     FEPDLYKSEM EVQDAELKAL LQSSASQETQ KKKKKKKRLP RLQRMPPVGK H
//