ID G7PJG4_MACFA Unreviewed; 655 AA.
AC G7PJG4;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 13-SEP-2023, entry version 37.
DE RecName: Full=RIMS-binding protein 2 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=EGM_03902 {ECO:0000313|EMBL:EHH66840.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1] {ECO:0000313|EMBL:EHH66840.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CE-4 {ECO:0000313|EMBL:EHH66840.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
CC -!- SIMILARITY: Belongs to the RIMBP family.
CC {ECO:0000256|ARBA:ARBA00010749}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM001286; EHH66840.1; -; Genomic_DNA.
DR AlphaFoldDB; G7PJG4; -.
DR eggNOG; KOG3632; Eukaryota.
DR Proteomes; UP000009130; Chromosome 11.
DR CDD; cd00063; FN3; 3.
DR CDD; cd12014; SH3_RIM-BP_1; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR040325; RIMBP1/2/3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR14234; RIM BINDING PROTEIN-RELATED; 1.
DR PANTHER; PTHR14234:SF18; RIMS-BINDING PROTEIN 2; 1.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 134..201
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 456..556
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 78..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 550..581
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 593..655
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 550..564
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 619..633
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EHH66840.1"
FT NON_TER 655
FT /evidence="ECO:0000313|EMBL:EHH66840.1"
SQ SEQUENCE 655 AA; 71222 MW; 93107AA5DD3B141C CRC64;
QSKVRELEEK CRTQSEQFNL LSRDLEKFRQ HAGKIDLLGG STVAPLDVST APGKPFPQFV
NGLATSLGKG QESAIGGGSA IGEYIRPLPQ PGDSPEPLSA KPTFLSRSGS PRCRSESDME
NERNSNTSKQ RYSGKVHLCV ARYSYNPFDG PNENPEAELP LTAGKYLYVY GDMDEDGFYE
GELLDGQRGL VPSNFVDFVQ DNESRLASTL GNEQDQNFIN HSGIGLEGEH ILDLHSPTHT
DVGITDNSAG TLDVNIDDIG EDIVPYPRKI TLIKQLAKSV IVGWEPPAVP PGWGTVSSYN
VLVDKETRMN LSLGSRTKAL IEKLNMAACT YRISVQCVTS RGSSDALQCT LLVGKDVVVA
PSHLRVDNIT QISAQLSWLP TNSNYSHVIF LNEEEFDIVK AARYKYQFFN LRPNMAYKVK
VLAKPHQMPW QLPLEQREKK EAFVEFSTLP AGPPAPPQDV TVQAGATPAT IRVSWRPPVL
TPSGLSNGAN VTGYGVYAKG QRVSFRWVRA DSTAVELVGV RSLEAKGVTV RTLSAQGESV
DSAVAAVPPE LLVPPTPHPR PAPQSKPLAS SGVPDTKDER LGPHARMDEA WEQSRAPGPV
HGHTLEPPAG PGRRSPSPSR ILPQPQGTPV STTVAKAMAR EAAQRVAESS RVRLW
//
