ID   G7PKQ3_MACFA            Unreviewed;      1316 AA.
AC   G7PKQ3;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   13-SEP-2023, entry version 39.
DE   RecName: Full=Tetratricopeptide repeat protein 21B {ECO:0008006|Google:ProtNLM};
GN   ORFNames=EGM_04019 {ECO:0000313|EMBL:EHH54912.1};
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1] {ECO:0000313|EMBL:EHH54912.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CE-4 {ECO:0000313|EMBL:EHH54912.1};
RX   PubMed=22002653; DOI=10.1038/nbt.1992;
RA   Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA   Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA   Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA   Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA   Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA   Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT   "Genome sequencing and comparison of two nonhuman primate animal models,
RT   the cynomolgus and Chinese rhesus macaques.";
RL   Nat. Biotechnol. 29:1019-1023(2011).
CC   -!- SIMILARITY: Belongs to the TTC21 family.
CC       {ECO:0000256|ARBA:ARBA00010935}.
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DR   EMBL; CM001287; EHH54912.1; -; Genomic_DNA.
DR   eggNOG; ENOG502QQAB; Eukaryota.
DR   Proteomes; UP000009130; Chromosome 12.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 5.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   InterPro; IPR040364; TTC21A/TTC21B.
DR   PANTHER; PTHR14699; STI2 PROTEIN-RELATED; 1.
DR   PANTHER; PTHR14699:SF1; TETRATRICOPEPTIDE REPEAT PROTEIN 21B; 1.
DR   Pfam; PF14559; TPR_19; 1.
DR   Pfam; PF13181; TPR_8; 3.
DR   SMART; SM00028; TPR; 18.
DR   SUPFAM; SSF81901; HCP-like; 1.
DR   SUPFAM; SSF48452; TPR-like; 4.
DR   PROSITE; PS50005; TPR; 3.
PE   3: Inferred from homology;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT   REPEAT          324..357
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          722..755
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          952..985
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ   SEQUENCE   1316 AA;  151026 MW;  175C74DF84300902 CRC64;
     MDSQELKTLI NYYCQERYFH HVLLVASEGI KRYGSDPVFR FYHAYGTLME GKTQEALREF
     EAIKNKQDVS LCSLIALIYA HKMSPNPDRE AILESDARVK EQRKGAGEKA LYHAGLFLWH
     IGRHDKAREY IDRMIKMSDG SKQGHVLKAW LDITRGKDPY TKKALKYFEE GLQDGNDTFA
     LLGKAQCLEM RQNYSGALET VNQIIVNFPS FLPSFVKKMK LQLALQDWDQ TVETAQWLLL
     QDSQNVEALR MQALYYVCRE GDIEKASTKL ENLGNALDAM EPQNAQLFYN ITLAFSRTCG
     RSQLILQKIQ TLLEKAFSLN PQQSEFATEL GYQMILQGRV KEALKWYKTA MTLDETSVSA
     LVGFIQCQLI EGQLQDADQQ LEFLNEIQQS IGKSAELIYL HAVLAMKKNK RQEEVINLLN
     DVLDTHFSQI ESLPLGIQYF EKLNPDFLLE IVTEYLSFCP MQPASPGQPL CPLLRRCVSV
     LETVVRTVPG LLQTVFLIAK VKYLSGDIEA AFNNLQHCLE HNPSYADAHL LLAQVYLSQE
     KVKLCSQSLE LCLSYDFKVR EYPLYHLIKA QSQKKMGEIA DAIKTLHMAM SLPGMKRIGA
     STKSKDRKTE VDTSHRLSIF LELIELHRLN GEQHEAAKVL QDAIHEFSGT SEEVRVAIAN
     ADLALAQGDI ERALSILQNV TAEQPYFIEA REKMANIYLK HRKDKMLYIT CFREIAERMA
     NPRSFLLLGD AYMNILEPEE AIVAYEQALN QNPKDGTLAS KMGKALIKTH NYSMAITYYE
     TALKSGQKNY LCYDLAELLL KLKWYDKAEK VLQHALAHEP VNELSALMED GRCQVLLAKV
     YSKMERPGDA ITALQQAREL QARVLKRVQM EQPDAVPAQK HLAAEICAEI AKHSVAQRDY
     EKAIKFYREA LVHYETDNKI MLELARLYLA QDDPDSCLRQ CALLLQSDQD NEAATMMMAD
     LMFRKQDYEQ AVFHLQQLLE RKPDNYMTLS RLIDLLRRCG KLEDVPRFFS MAEKRNSRAK
     LEPGFQYCKG LYLWYTGEPN DALRHFNKAR KDRDWGQNAL YNMIEICLNP DNETIGGEVF
     ENLDGDLGNS TEKQESVQLA VRTAEKLLKE LKPQTVQGHV QLRIMENYCL MATKQKSNVE
     QALNTFTEIA ASEKDHIPAL LGMATAYMIL KQTPRARNQL KRIVKMNWNA IDAEEFEKSW
     LLLADIYIQS AKYDMAEELL KRCLRHNRSC CKAYEYMGYI MEKEQAYTDA ALNYEMAWKY
     SNRTNPAVGY KLAFNYLKAK RYVDSIDICH QVLEAHPTYP KIRKDILDKA RASLRP
//