ID G7PLU7_MACFA Unreviewed; 952 AA.
AC G7PLU7;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Elastin microfibril interfacer 1 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=EGM_04653 {ECO:0000313|EMBL:EHH55442.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1] {ECO:0000313|EMBL:EHH55442.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CE-4 {ECO:0000313|EMBL:EHH55442.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
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DR EMBL; CM001288; EHH55442.1; -; Genomic_DNA.
DR AlphaFoldDB; G7PLU7; -.
DR eggNOG; ENOG502RIZH; Eukaryota.
DR Proteomes; UP000009130; Chromosome 13.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0048583; P:regulation of response to stimulus; IEA:UniProt.
DR Gene3D; 2.60.120.40; -; 1.
DR InterPro; IPR001073; C1q_dom.
DR InterPro; IPR008160; Collagen.
DR InterPro; IPR011489; EMI_domain.
DR InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR PANTHER; PTHR15427; EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER; 1.
DR PANTHER; PTHR15427:SF1; EMILIN-1; 1.
DR Pfam; PF00386; C1q; 1.
DR Pfam; PF01391; Collagen; 1.
DR Pfam; PF07546; EMI; 1.
DR SUPFAM; SSF49842; TNF-like; 1.
DR PROSITE; PS50871; C1Q; 1.
DR PROSITE; PS51041; EMI; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..952
FT /note="Elastin microfibril interfacer 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003502669"
FT DOMAIN 56..131
FT /note="EMI"
FT /evidence="ECO:0000259|PROSITE:PS51041"
FT DOMAIN 869..952
FT /note="C1q"
FT /evidence="ECO:0000259|PROSITE:PS50871"
FT REGION 132..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 258..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 383..402
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 814..867
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 309..336
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 678..705
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 821..841
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 952
FT /evidence="ECO:0000313|EMBL:EHH55442.1"
SQ SEQUENCE 952 AA; 100000 MW; B28B22D2426E5ECC CRC64;
MAPRTLWSCY LCCLLTAAAG AASYPPRGYS LYTGSGGALS PGGPQAQSAP RPASRHRNWC
AYVVTRTVSC VLEDGVETYV KYQPCAWGQP QCPQSIMYRR FLRPRYRVAY KTVTDMEWRC
CQGYGGDDCA ESPAPALGPA SSTPRPLPRP ARPNLSGSSA GSPLSGLGGE GPGESEKVQQ
LEEQVQSLTK ELQGLRGVLQ GLSGRLAEDV QRAVETAFNG RQQPADAAAR PGVHETLNEI
QHQLQLLDTR VSTHDQELGQ LNNHHGGSSS RGGSRAPAPA SAPPGPSEEL LRQLEQRLQE
SCSVCLAGLD GFRRQQQEDR ERLRALEKLL ASVEGQQRHL PGLAVGRRPP QECCSPELGR
RLAELERRLD VVAGSVTVLS GRRGTELGGA AGQGGHPPGY TSLASRLSRL EDRFNSTLGP
SEEQEESWPG APGGLSHWLP AARGRLEQLG ALLANVSGEL GGRLDLLEEQ VAGAMQACGQ
LCSGAPGEQD SQVSEILSAL ERRVLDSEGQ LRLVGSGLHT VEAAKAAGEA RQAMLEGLQG
VVGRLQDRVD AQDETAAEFT LRLNLTSARL GQLEGLLQAH GDEGCGACGG VQEELGRLRD
GVERCSCPLL PPRGPGAGPG VGGPSRGPLD GFSVFGGSSG SALQALQGEL SEVILTFSSL
NDSLNELQTT VEGQGADLAD LGATKDRIIS EINRLQQEAT EHATESEERF RGLEEGQAQA
GQCPSLEGRL GRLEGVCERL DTVAGGLQGL REGLSRHMAG LWAGLRETNT TSQMQAALLE
KLVGGQAGLG RRLGALNSSL QLLEDRLHQL SLKDLTGPAG EAGPPGPPGL QGPPGPAGPP
GSPGKDGQEG PIGPPGPQGE QGVEGAPAAP VPRVAFSAAL SLPRSEPGTV PFDRVLLNDG
GYYDPETGVF TAPLAGRYLL SAVLTGHRHE KVEAVLSRSN QGVARVDSGG YE
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