ID   G7PMV7_MACFA            Unreviewed;       860 AA.
AC   G7PMV7;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   RecName: Full=CNH domain-containing protein {ECO:0000259|PROSITE:PS50219};
GN   ORFNames=EGM_05076 {ECO:0000313|EMBL:EHH55802.1};
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1] {ECO:0000313|EMBL:EHH55802.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CE-4 {ECO:0000313|EMBL:EHH55802.1};
RX   PubMed=22002653; DOI=10.1038/nbt.1992;
RA   Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA   Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA   Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA   Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA   Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA   Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT   "Genome sequencing and comparison of two nonhuman primate animal models,
RT   the cynomolgus and Chinese rhesus macaques.";
RL   Nat. Biotechnol. 29:1019-1023(2011).
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DR   EMBL; CM001288; EHH55802.1; -; Genomic_DNA.
DR   AlphaFoldDB; G7PMV7; -.
DR   eggNOG; KOG2063; Eukaryota.
DR   Proteomes; UP000009130; Chromosome 13.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR000547; Clathrin_H-chain/VPS_repeat.
DR   InterPro; IPR001180; CNH_dom.
DR   InterPro; IPR032914; Vam6/VPS39/TRAP1.
DR   InterPro; IPR019452; VPS39/TGF_beta_rcpt-assoc_1.
DR   InterPro; IPR019453; VPS39/TGF_beta_rcpt-assoc_2.
DR   PANTHER; PTHR12894; CNH DOMAIN CONTAINING; 1.
DR   PANTHER; PTHR12894:SF27; TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1; 1.
DR   Pfam; PF00637; Clathrin; 1.
DR   Pfam; PF00780; CNH; 1.
DR   Pfam; PF10366; Vps39_1; 1.
DR   Pfam; PF10367; Vps39_2; 1.
DR   PROSITE; PS50236; CHCR; 1.
DR   PROSITE; PS50219; CNH; 1.
PE   4: Predicted;
FT   DOMAIN          24..297
FT                   /note="CNH"
FT                   /evidence="ECO:0000259|PROSITE:PS50219"
SQ   SEQUENCE   860 AA;  97306 MW;  9162C5301F2F493A CRC64;
     MMNIKAFTLV SAVERELLMG DKERINIECV ECCGRDLYVG TNDCFVYHFL LEERPVPAGP
     ATFTATKQLH RHLGFKKPVN ELRAASALNR LLVLCDNSIS LVNMLNLEPV PSGARIKGAA
     TFALNENPVS GDPFCVEVCI ISVKRRTIQM FLVYEDRVQI VKEVSTSEQP LAVAVDGHFL
     CLALTTQYII HNYSTGVSQD LFPYCSEERP PIVKRIGRQE FLLAGPGGLG MFATVAGISQ
     RAPVHWSENV IGAAVCFPYV IALDDEFITV HSMLDQQQKQ TLPFKEGHIL QDFEGRVIVA
     TSKGVYILVP LPLEKQIQDL LASRRVEEAL VLAKGARRNI PKDKFQVMYR RILQQAGFIQ
     FAQLQFLEAK ELFRSGQLDV RELISLYPFL LPTSSSFTRS HPPLHEYADL NQLTQGDQEK
     MAKCKRFLMS YLNEVRSTEV ANGYKEDIDT ALLKLYAEAD HDSLLDLLVT ENFCLLTDSA
     AWLEKHKKYF ALGLLYHYNN QDAAAVQLWV NIVNGDVQDS TRSDLYEYIV DFLTYCLDEE
     LVWAYADWVL QKSEEVGVQV FTKRPLDEQQ KNSFNPDDII NCLKKYPKAL VKYLEHLVID
     KRLQKEEYHT HLAVLYLEEV LQQRASTSGK GAEASETQAK LRRLLQKSDL YRVHFLLERL
     RGAGLPMESA ILHGKLGEHE KALHILVHEL RDFAAAEDYC LWCSEGRDPP HRQHLFHTLL
     AIYLRAGPAA HELAVAAVDL LNHHATEFDA AQVLQMLPDT WSVQLLCPFL MGAMRDSVHA
     RRTMQVALGL ARSENLIYTY DKMKLKGSSI RLSDKKLCQI CQNPFCEPVF VRYPNGGLVH
     THCAASRHTN PSSSSPGTRT
//