ID G7PTU6_MACFA Unreviewed; 634 AA.
AC G7PTU6;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=RING finger protein 112 {ECO:0008006|Google:ProtNLM};
GN ORFNames=EGM_07506 {ECO:0000313|EMBL:EHH57795.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1] {ECO:0000313|EMBL:EHH57795.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CE-4 {ECO:0000313|EMBL:EHH57795.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
CC -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC superfamily. GB1/RHD3 GTPase family. {ECO:0000256|PROSITE-
CC ProRule:PRU01052}.
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DR EMBL; CM001291; EHH57795.1; -; Genomic_DNA.
DR AlphaFoldDB; G7PTU6; -.
DR eggNOG; KOG2037; Eukaryota.
DR eggNOG; KOG2177; Eukaryota.
DR Proteomes; UP000009130; Chromosome 16.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR CDD; cd01851; GBP; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR030386; G_GB1_RHD3_dom.
DR InterPro; IPR015894; Guanylate-bd_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR10751; GUANYLATE BINDING PROTEIN; 1.
DR PANTHER; PTHR10751:SF1; RING FINGER PROTEIN 112; 1.
DR Pfam; PF02263; GBP; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51715; G_GB1_RHD3; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 58..99
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 167..400
FT /note="GB1/RHD3-type G"
FT /evidence="ECO:0000259|PROSITE:PS51715"
SQ SEQUENCE 634 AA; 68680 MW; 66BA4153CBA68697 CRC64;
MPRPALSVTS FCHRLGKRAK RKQSFMGNSG NSWSHTPFPK LELGLGPRPM APRELPTCSI
CLERLREPIS LECGHDFCIR CFSTHRVPGC EPPCCPECRK ICKQKRGLRS LGEKMKLLPQ
RPLPPALQET CPVRAEPLLL VRVNASGGLI LRMGAINRCL KHPLARDTPV CLLAVLGEQH
SGKSFLLNHL LQGLPGLESG EGGWPRGGEA SLQGCRWGAN GLARGIWMWS HPFLLGKEGK
KVAVFLVDTG DAMSPELSRE TRIKLCALTT MLSSYQILNT CQELKDTDLD YLEMFVHVAE
VMGKHYGMVP IQHLDLLVRD SSHPNKAGQG HVGNIFQRLS GRYPKVQELL QGKRARCCLL
PAPGRRWMNQ GHASPGGEYT DDDFCHLLGA YVSDVLSAAP QHAKSRCQGY WNEGRAVARG
DRRLLTGQQL AQEIKNLSGW MGRTGPGFTS PDEMAAQLHD LRKVEAAKRE FEEYVRQQDI
ATKRIFSALR VLPDTMRNLL STQKDAILAR HGVALLCKGR DQTLEALEAE LQATAKAFMD
SYTMRFCGHL AAVGGAVGAG LMGLAGGVVG AGMAAAALAA EAGMVAAGAA VGATGAAVVG
GGVGAGLAAT VGCMEKEEDE RVLEGDREPL LQEE
//
