ID G7PUQ8_MACFA Unreviewed; 215 AA.
AC G7PUQ8;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHH58107.1};
GN ORFNames=EGM_07891 {ECO:0000313|EMBL:EHH58107.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1] {ECO:0000313|EMBL:EHH58107.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CE-4 {ECO:0000313|EMBL:EHH58107.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
CC -!- FUNCTION: In the hair cortex, hair keratin intermediate filaments are
CC embedded in an interfilamentous matrix, consisting of hair keratin-
CC associated proteins (KRTAP), which are essential for the formation of a
CC rigid and resistant hair shaft through their extensive disulfide bond
CC cross-linking with abundant cysteine residues of hair keratins. The
CC matrix proteins include the high-sulfur and high-glycine-tyrosine
CC keratins. {ECO:0000256|ARBA:ARBA00003327}.
CC -!- SUBUNIT: Interacts with hair keratins. {ECO:0000256|ARBA:ARBA00011662}.
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DR EMBL; CM001291; EHH58107.1; -; Genomic_DNA.
DR AlphaFoldDB; G7PUQ8; -.
DR Proteomes; UP000009130; Chromosome 16.
DR GO; GO:0005829; C:cytosol; IEA:UniProt.
DR GO; GO:0045095; C:keratin filament; IEA:InterPro.
DR InterPro; IPR002494; KAP.
DR PANTHER; PTHR23262; KERATIN ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR23262:SF183; KERATIN-ASSOCIATED PROTEIN 4-11-RELATED; 1.
DR Pfam; PF13885; Keratin_B2_2; 2.
PE 4: Predicted;
KW Keratin {ECO:0000256|ARBA:ARBA00022744};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
SQ SEQUENCE 215 AA; 22957 MW; 408773121E53B8BA CRC64;
MNNSCCGSVC SDQSCGQDLC QESCCRPSCC QTTCCRTTCC RPSCCVSSCC RPQCCQSVCC
QPTCCRPSCC QTTCCRTTCC HPSCCVSSCC SPHCCVSSCC RPQCCQSVCC QPTCCRPSCC
QTTCCRTTCC RPSCCVSSCC RPQCCQSVCC QPTCCRPSCC ISSCCRPSCC ESSCCRPCCC
LRPVCGRVSC HTTCYRPTCV ISTCPRPLCC ASSCC
//
