ID G7PV65_MACFA Unreviewed; 284 AA.
AC G7PV65;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Guanine nucleotide-binding protein subunit alpha-13 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=EGM_08070 {ECO:0000313|EMBL:EHH58264.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1] {ECO:0000313|EMBL:EHH58264.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CE-4 {ECO:0000313|EMBL:EHH58264.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
CC -!- SIMILARITY: Belongs to the G-alpha family. G(12) subfamily.
CC {ECO:0000256|ARBA:ARBA00010405}.
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DR EMBL; CM001291; EHH58264.1; -; Genomic_DNA.
DR AlphaFoldDB; G7PV65; -.
DR eggNOG; KOG0082; Eukaryota.
DR Proteomes; UP000009130; Chromosome 16.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0001664; F:G protein-coupled receptor binding; IEA:InterPro.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR GO; GO:0007266; P:Rho protein signal transduction; IEA:InterPro.
DR CDD; cd00066; G-alpha; 1.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000469; Gprotein_alpha_12/13.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR PANTHER; PTHR10218:SF85; GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA-13; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR PRINTS; PR00440; GPROTEINA12.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EHH58264.1"
FT NON_TER 284
FT /evidence="ECO:0000313|EMBL:EHH58264.1"
SQ SEQUENCE 284 AA; 33472 MW; EFE4F41965356E72 CRC64;
KGMRVLVDAR EKLHIPWGDN SNQQHGDKMM SFDTRAPMAA QGMVETRVFL QYLPAIRALW
ADSGIQNAYD RRREFQLGES VKYFLDNLDK LGEPDYIPSQ QDILLARRPT KGIHEYDFEI
KNVPFKMVDV GGQRSERKRW FECFDSVTSI LFLVSSSEFD QVLMEDRLTN RLTESLNIFE
TIVNNRVFSN VSIILFLNKT DLLEEKVQIV SIKDYFLEFE GDPHCLRDVQ KFLVECFRNK
RRDQQQKPLY HHFTTAINTE NIRLVFRDVK DTILHDNLKQ LMLQ
//
