ID G7PWM3_MACFA Unreviewed; 429 AA.
AC G7PWM3;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 08-NOV-2023, entry version 41.
DE SubName: Full=Protein arginine N-methyltransferase 2 {ECO:0000313|EMBL:EHH58846.1};
GN ORFNames=EGM_08795 {ECO:0000313|EMBL:EHH58846.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1] {ECO:0000313|EMBL:EHH58846.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CE-4 {ECO:0000313|EMBL:EHH58846.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
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DR EMBL; CM001293; EHH58846.1; -; Genomic_DNA.
DR AlphaFoldDB; G7PWM3; -.
DR eggNOG; KOG1499; Eukaryota.
DR Proteomes; UP000009130; Chromosome 18.
DR GO; GO:0016274; F:protein-arginine N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd11806; SH3_PRMT2; 1.
DR Gene3D; 2.70.160.11; Hnrnp arginine n-methyltransferase1; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR025799; Arg_MeTrfase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR007848; Small_mtfrase_dom.
DR PANTHER; PTHR11006; PROTEIN ARGININE N-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11006:SF92; PROTEIN ARGININE N-METHYLTRANSFERASE 2; 1.
DR Pfam; PF05175; MTS; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51678; SAM_MT_PRMT; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|PROSITE-ProRule:PRU01015,
KW ECO:0000313|EMBL:EHH58846.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01015};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192};
KW Transferase {ECO:0000256|PROSITE-ProRule:PRU01015,
KW ECO:0000313|EMBL:EHH58846.1}.
FT DOMAIN 30..89
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 429 AA; 48950 MW; ACFDD07400D92018 CRC64;
MATSGDCPRS ESQEEEPAEY SEAGLLQEGV QPEEFVAIAD YAATDETQLS FLRGEKILIL
RQTTADWWWG ERAGYCGYIP ANHVGKEMDE YDPEDTWQDE EYFGSYGTLK LHLEMLADQP
RTTKYHSVIL QNKESLTDKV ILDVGCGTGI ISLFCAHYAR PKAVYAVEAS EMAQHTGQLV
LQNGFADIIT VFQQKVEDVV LPEKVDVLVS EWMGTCLLFE FMIESILYAR DAWLKEDGVI
WPTMAALHLV PCSADKDYRS KVLFWDNAYE FNLSALKSLA IKEFFSKPKY NHILKPEDCL
SEPCTILQLD MRTVQISDLE HLQNQINYIS FHYGICITVF FHVFLATLHD RTVKIPSTNP
CLITHWKQTL FMMDDPVPVH TGDVVTGSVV LQRNPVWRRH MSVALSWAVT SRQDPTSQKV
GEKVFPIWR
//
