ID G7PY99_MACFA Unreviewed; 881 AA.
AC G7PY99;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=Minor histocompatibility protein HA-1 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=EGM_09006 {ECO:0000313|EMBL:EHH59015.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1] {ECO:0000313|EMBL:EHH59015.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CE-4 {ECO:0000313|EMBL:EHH59015.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
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DR EMBL; CM001294; EHH59015.1; -; Genomic_DNA.
DR eggNOG; KOG1453; Eukaryota.
DR Proteomes; UP000009130; Chromosome 19.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR15228:SF18; RHO GTPASE-ACTIVATING PROTEIN 45; 1.
DR PANTHER; PTHR15228; SPERMATHECAL PHYSIOLOGY VARIANT; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077, ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771};
KW Zinc {ECO:0000256|ARBA:ARBA00022771};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 238..505
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 500..721
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 59..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 211..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 482..565
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 804..859
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 404..460
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 16..37
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 539..553
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 817..839
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 841..857
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EHH59015.1"
SQ SEQUENCE 881 AA; 96184 MW; 62957A6CD5D51CCF CRC64;
LPRKDGVDAV FPGPSLEPST GSSSAKATGT LKRPTSLSRH ASAAGFPLSG AASWTLGRSH
RSPLTAASPG EQPTEGAGPD GVEDISHLLA DVARFAEGLE KLKECVLHDD LLEARRPLAH
ECLGEALRVM RQIISKYPLL NTVETLTAAG TLIAKVKAFH YESNNDLEKQ EFEKALETIA
VAFSSTVSEF LMGEVDSSTL LAVPPGDSSQ SMESLYGPGS EGTPPGLDDC DAGCLPAEEV
DVLLQRCEGG VDAALLYAKN MAKYMKDLIS YLEKRTTLEM EFAKGLQKIC HNCRQSVMQE
PHMPLLSIYS LALEQDLEFG HGMVQAVGTL QTQTFMQPLT LRRLEHEKRR KEIKEAWHQE
AESNLRKAKQ GYTQRCEDHD KARFLVAKAE EEQAGTTLGA GSTVTKTLDK RRRLEEEAKN
KAEEAMATYR TCVADAKTQK QELEDTKVTA LRQIQEVIRQ SDQTIKSSPV LRARKSSFNV
SDVAGPEAAG SPPEEGIEGA PAKERRAGRG HQVHKSWPLS ISDSDSGLDT GPGTGDFKKF
ERTSSSGTMS STEELVDPEG GAGASAFEQA DLNGMTPELP VAVPSGPFRH EGLSKAARTH
RLRKLRTPAK CRECNSYVYF QGAECEEXXX XXXXXXXXXX XXXXXXXXXX XSLQYLLRHL
RRIVEVEQDN KMTPGNLGIV FGPTLLRPRP TEATVSLSSL VDYPHQARVI ETLIVHYGLV
FEEEPEETPG DQDESSSQRA EVVIQVPYVE AGEGVVYPLQ EAAEDGCRES RVVSNDSDSD
LEEASELLSS SEASALRRLS LLEQQQSEAS LEEASGSHSG SEERLEATAR EDGDEDDPAR
QLSGFNTNQS NNVLQAPLPT MRLRGGRIAL GSCRERRPEF V
//
