ID G7PZ33_MACFA Unreviewed; 635 AA.
AC G7PZ33;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 22-FEB-2023, entry version 22.
DE SubName: Full=PML-RARA-regulated adapter molecule 1 {ECO:0000313|EMBL:EHH59151.1};
DE Flags: Fragment;
GN ORFNames=EGM_09199 {ECO:0000313|EMBL:EHH59151.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1] {ECO:0000313|EMBL:EHH59151.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CE-4 {ECO:0000313|EMBL:EHH59151.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
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DR EMBL; CM001294; EHH59151.1; -; Genomic_DNA.
DR AlphaFoldDB; G7PZ33; -.
DR eggNOG; ENOG502SS22; Eukaryota.
DR Proteomes; UP000009130; Chromosome 19.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:InterPro.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR043443; FYB1/2-like.
DR InterPro; IPR029294; hSH3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR PANTHER; PTHR16830:SF11; PML-RARA-REGULATED ADAPTER MOLECULE 1; 1.
DR PANTHER; PTHR16830; SH2 CONTAINING ADAPTOR PRAM-1 RELATED; 1.
DR Pfam; PF14603; hSH3; 1.
DR PRINTS; PR01217; PRICHEXTENSN.
DR SUPFAM; SSF50044; SH3-domain; 1.
PE 4: Predicted;
FT DOMAIN 576..635
FT /note="Helically-extended SH3"
FT /evidence="ECO:0000259|Pfam:PF14603"
FT REGION 1..575
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..64
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 65..115
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 438..464
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 525..539
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EHH59151.1"
FT NON_TER 635
FT /evidence="ECO:0000313|EMBL:EHH59151.1"
SQ SEQUENCE 635 AA; 70586 MW; D29F20805984C12C CRC64;
VAHHLPAAME SHQDFRSIKA KFQASQPEPS DLPKKPPKPE FSKLKKFPQP ELSEHLKKPP
PPEFTDLPKK PPPPEVTDLP KKPPPPEFTD LPKKPPPPEV TDLPKKPPPP EFTDLPKKPS
KLEFSDVSKK FPQLEATPFP RKPPQPEVGE APVKASLLEP NTPVRKPQQS DELSHPARPP
SEPKSSAFPR KLWQPEASEA TPKPPQPEFS TFPKKPAQPE VNMHPKKPPQ PQADGLPKKS
VPQPEFSEAA QTPLWKPQSG EPKHDSSAFP RKASQPPLSD FPKKPPQPEL GDLTRTSSEP
EVSVLPKRPR PAEFKALSKK PPQPELGGLP RTSSEPEFNS LPRKLLQPDR RGPPRKFSQP
EPNAVLKRHP QPEFFGDLPR KPLLPSSASE SSLPAAVAGS SSRHPLSPGF GVAGTRRWRS
GGLVHSGGAR PGLRPSHPPR RRPLPAASSL GPPPAKPPLP PGPVDMQSFR RRSAASTDLR
RTRSAATLHF QARQPEDIPP IPDEIYELYD DVEPRDDSSP SPKGRDEAPS VQQVTRRPPQ
DSALRREKDP QPQQLPPMDP KLQKQLRKAE KAEREFRKKF KFEGEIVVHT KMMIDPNAKT
RRGGGKHLGI RRGEILEVIE FTSNEEMLCR NPKGK
//
