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Database: UniProt
Entry: G7QBY3_9DELT
LinkDB: G7QBY3_9DELT
Original site: G7QBY3_9DELT 
ID   G7QBY3_9DELT            Unreviewed;       453 AA.
AC   G7QBY3;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   16-JAN-2019, entry version 46.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   ORFNames=DFW101_0001 {ECO:0000313|EMBL:EHJ46018.1};
OS   Desulfovibrio sp. FW1012B.
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfovibrionales;
OC   Desulfovibrionaceae; Desulfovibrio.
OX   NCBI_TaxID=644968 {ECO:0000313|EMBL:EHJ46018.1, ECO:0000313|Proteomes:UP000004662};
RN   [1] {ECO:0000313|Proteomes:UP000004662}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FW1012B {ECO:0000313|Proteomes:UP000004662};
RX   PubMed=25767232;
RA   Ramsay B.D., Hwang C., Woo H.L., Carroll S.L., Lucas S., Han J.,
RA   Lapidus A.L., Cheng J.F., Goodwin L.A., Pitluck S., Peters L.,
RA   Chertkov O., Held B., Detter J.C., Han C.S., Tapia R., Land M.L.,
RA   Hauser L.J., Kyrpides N.C., Ivanova N.N., Mikhailova N., Pagani I.,
RA   Woyke T., Arkin A.P., Dehal P., Chivian D., Criddle C.S., Wu W.,
RA   Chakraborty R., Hazen T.C., Fields M.W.;
RT   "High-Quality Draft Genome Sequence of Desulfovibrio carbinoliphilus
RT   FW-101-2B, an Organic Acid-Oxidizing Sulfate-Reducing Bacterium
RT   Isolated from Uranium(VI)-Contaminated Groundwater.";
RL   Genome Announc. 3:0-0(2015).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|RuleBase:RU000577,
CC       ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC       {ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CM001368; EHJ46018.1; -; Genomic_DNA.
DR   RefSeq; WP_009179477.1; NZ_CM001368.1.
DR   STRING; 644968.DFW101_0001; -.
DR   EnsemblBacteria; EHJ46018; EHJ46018; DFW101_0001.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   Proteomes; UP000004662; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00756129};
KW   Complete proteome {ECO:0000313|Proteomes:UP000004662};
KW   Cytoplasm {ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|RuleBase:RU004227,
KW   ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00756117};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004662}.
FT   DOMAIN      147    286       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      362    430       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
SQ   SEQUENCE   453 AA;  50570 MW;  85C0F8576B984D32 CRC64;
     METIWPRIKK LLEQTLSPGL YNLWIKPLTA RARDGVLELA APNAFVASWV RERLADSVVE
     AAAVVMGSRP QLVVTEAART ADAPAAAPAA TAPRPARAPR SLTLPMAPKA PDLGNDRFRF
     SYDEFVVGPS NELAYVASQG ICDMSLSADQ LFISSAPGLG KTHLIQAMGK RLSHTGGEDG
     RNLRVAYLSA EEFANRLVIA LKTRQVEKFK AAFRENVDVL LLEDIHFFRD KPRIQDELLN
     TLIALNSRGC RLVFTSSFLP RDLAGLDAQL LSRISSGFLT VIDKPDLATR KRILERKAAV
     HQVLLPDEVS TLLADRLHAD VRQLESCLQN LALKARLLNC RISVDLAWDV LRHYDLEARS
     LTLEDIVEYV CDVYRLSADQ LVSKSRKRQY VLARNTAFLL ARQHTDMSLV DIGNRFNRRH
     STVVKGITSL ERHLSLRTPL GRELERTIES VRA
//
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