ID G7W6X6_DESOD Unreviewed; 210 AA.
AC G7W6X6;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Methyltransferase cognate corrinoid protein {ECO:0000313|EMBL:AET69833.1};
GN OrderedLocusNames=Desor_4414 {ECO:0000313|EMBL:AET69833.1};
OS Desulfosporosinus orientis (strain ATCC 19365 / DSM 765 / NCIMB 8382 / VKM
OS B-1628 / Singapore I) (Desulfotomaculum orientis).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC Desulfosporosinus.
OX NCBI_TaxID=768706 {ECO:0000313|EMBL:AET69833.1, ECO:0000313|Proteomes:UP000006346};
RN [1] {ECO:0000313|Proteomes:UP000006346}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19365 / DSM 765 / NCIMB 8382 / VKM B-1628
RC {ECO:0000313|Proteomes:UP000006346};
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Teshima H., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Pester M.,
RA Spring S., Ollivier B., Rattei T., Klenk H.-P., Wagner M., Loy A.,
RA Woyke T.;
RT "Complete sequence of Desulfosporosinus orientis DSM 765.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AET69833.1, ECO:0000313|Proteomes:UP000006346}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19365 / DSM 765 / NCIMB 8382 / VKM B-1628
RC {ECO:0000313|Proteomes:UP000006346};
RX PubMed=23105050; DOI=10.1128/JB.01392-12;
RA Pester M., Brambilla E., Alazard D., Rattei T., Weinmaier T., Han J.,
RA Lucas S., Lapidus A., Cheng J.F., Goodwin L., Pitluck S., Peters L.,
RA Ovchinnikova G., Teshima H., Detter J.C., Han C.S., Tapia R., Land M.L.,
RA Hauser L., Kyrpides N.C., Ivanova N.N., Pagani I., Huntmann M., Wei C.L.,
RA Davenport K.W., Daligault H., Chain P.S., Chen A., Mavromatis K.,
RA Markowitz V., Szeto E., Mikhailova N., Pati A., Wagner M., Woyke T.,
RA Ollivier B., Klenk H.P., Spring S., Loy A.;
RT "Complete genome sequences of Desulfosporosinus orientis DSM765T,
RT Desulfosporosinus youngiae DSM17734T, Desulfosporosinus meridiei DSM13257T,
RT and Desulfosporosinus acidiphilus DSM22704T.";
RL J. Bacteriol. 194:6300-6301(2012).
CC -!- SIMILARITY: Belongs to the methylamine corrinoid protein family.
CC {ECO:0000256|ARBA:ARBA00010854}.
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DR EMBL; CP003108; AET69833.1; -; Genomic_DNA.
DR RefSeq; WP_014186640.1; NC_016584.1.
DR AlphaFoldDB; G7W6X6; -.
DR STRING; 768706.Desor_4414; -.
DR KEGG; dor:Desor_4414; -.
DR PATRIC; fig|768706.3.peg.4485; -.
DR eggNOG; COG5012; Bacteria.
DR HOGENOM; CLU_082102_2_0_9; -.
DR OrthoDB; 9783599at2; -.
DR Proteomes; UP000006346; Chromosome.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0050897; F:cobalt ion binding; IEA:InterPro.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0015948; P:methanogenesis; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02070; corrinoid_protein_B12-BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 1.10.1240.10; Methionine synthase domain; 1.
DR InterPro; IPR003759; Cbl-bd_cap.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR012741; Corrinoid_p.
DR InterPro; IPR036594; Meth_synthase_dom.
DR NCBIfam; TIGR02370; pyl_corrinoid; 1.
DR PANTHER; PTHR45833; METHIONINE SYNTHASE; 1.
DR PANTHER; PTHR45833:SF1; METHIONINE SYNTHASE; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF02607; B12-binding_2; 1.
DR SMART; SM01018; B12-binding_2; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF47644; Methionine synthase domain; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51337; B12_BINDING_NTER; 1.
PE 3: Inferred from homology;
KW Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000313|EMBL:AET69833.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006346};
KW Transferase {ECO:0000313|EMBL:AET69833.1}.
FT DOMAIN 1..88
FT /note="B12-binding N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51337"
FT DOMAIN 88..210
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
SQ SEQUENCE 210 AA; 22076 MW; 7B565FB3637818BC CRC64;
MADFESLSQS VISGKATQVK EKVTAMLEAG VNPLDIINEG LIGGMNVVGP RFKSGEMFVP
EVLMSAKAMA AGIEIIKPLI ADQDIPSAGK VVIGTVKGDL HDIGKNLVAM MIESGGYSVV
DVGVDISPEK FIEAVREHKP SIIGMSALLT TTMLNMKDTI DLLKEEGLRD QVKVMVGGAP
VSKDFANEIG ADGFAPDAAS AVELCKKFLA
//
