ID G7WH21_DESOD Unreviewed; 1022 AA.
AC G7WH21;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Cation/multidrug efflux pump {ECO:0000313|EMBL:AET69529.1};
GN OrderedLocusNames=Desor_4089 {ECO:0000313|EMBL:AET69529.1};
OS Desulfosporosinus orientis (strain ATCC 19365 / DSM 765 / NCIMB 8382 / VKM
OS B-1628 / Singapore I) (Desulfotomaculum orientis).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC Desulfosporosinus.
OX NCBI_TaxID=768706 {ECO:0000313|EMBL:AET69529.1, ECO:0000313|Proteomes:UP000006346};
RN [1] {ECO:0000313|Proteomes:UP000006346}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19365 / DSM 765 / NCIMB 8382 / VKM B-1628
RC {ECO:0000313|Proteomes:UP000006346};
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Teshima H., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Pester M.,
RA Spring S., Ollivier B., Rattei T., Klenk H.-P., Wagner M., Loy A.,
RA Woyke T.;
RT "Complete sequence of Desulfosporosinus orientis DSM 765.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AET69529.1, ECO:0000313|Proteomes:UP000006346}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19365 / DSM 765 / NCIMB 8382 / VKM B-1628
RC {ECO:0000313|Proteomes:UP000006346};
RX PubMed=23105050; DOI=10.1128/JB.01392-12;
RA Pester M., Brambilla E., Alazard D., Rattei T., Weinmaier T., Han J.,
RA Lucas S., Lapidus A., Cheng J.F., Goodwin L., Pitluck S., Peters L.,
RA Ovchinnikova G., Teshima H., Detter J.C., Han C.S., Tapia R., Land M.L.,
RA Hauser L., Kyrpides N.C., Ivanova N.N., Pagani I., Huntmann M., Wei C.L.,
RA Davenport K.W., Daligault H., Chain P.S., Chen A., Mavromatis K.,
RA Markowitz V., Szeto E., Mikhailova N., Pati A., Wagner M., Woyke T.,
RA Ollivier B., Klenk H.P., Spring S., Loy A.;
RT "Complete genome sequences of Desulfosporosinus orientis DSM765T,
RT Desulfosporosinus youngiae DSM17734T, Desulfosporosinus meridiei DSM13257T,
RT and Desulfosporosinus acidiphilus DSM22704T.";
RL J. Bacteriol. 194:6300-6301(2012).
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DR EMBL; CP003108; AET69529.1; -; Genomic_DNA.
DR RefSeq; WP_014186336.1; NC_016584.1.
DR AlphaFoldDB; G7WH21; -.
DR STRING; 768706.Desor_4089; -.
DR KEGG; dor:Desor_4089; -.
DR PATRIC; fig|768706.3.peg.4143; -.
DR eggNOG; COG0841; Bacteria.
DR HOGENOM; CLU_002755_1_2_9; -.
DR OrthoDB; 9757876at2; -.
DR Proteomes; UP000006346; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF18; CATION EFFLUX SYSTEM PROTEIN; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006346};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 335..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 431..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 466..490
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 523..545
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 854..873
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 880..900
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 906..927
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 955..974
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 980..1007
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1022 AA; 112567 MW; 2CEDC32AF96DA782 CRC64;
MEKGFIYQVI NNRRFTLFFT FIALLLGLYS YYIIPKQESP NVHAPYAIIK TIYPGAEPED
VEKLVTKPIE DKIIEVPGYK TSSSYSRNSI SIVVLELEND ADVDKSWADL RRYMDDLQSS
LPSECQKIDI NTDLADTPGM ILSLSGDQYS YEQLSDFADQ FKNELSNVKG ISRFEVTGVQ
NKEARVEVNT ALLNQYDLSL EDIVNVLKLQ NVDIPVGSLN NENTKINVSV PGSFDSLQDI
ENCVVSVSKT TGAIVHLKDI AHVSWKLSDS TTRIRENGHN AILLSAYFSD NNNIVLIGKD
VQAKLQQLKE QLPSGLKVDE VTYQPTSVNQ SVTNFFENLL EGIALVLVVV FLGMGLKNAI
VASTAVPLSI LIAFCAMYLL KIRVHEISIA ALIIALGMLV DDAIVIIDSI QVLIDQGMEK
MEACILGTKR AVLPVFTATL TTAAAFAPML FVPGPAGEFL HTLPEVVILS IAASFIVAIF
VTPTLAYIFF AKLKAEKIQK RSPVKSFYQG FLAIGMKYKK TTLFLALSSL VLIVLLAFKL
PVMFFPKADV NMFYIDIHAE TSADLDNTDR VAQQVEKMIA GQKEVLTYTT SIGEGLPKFY
LTVGQSSQSQ DYAQILLKVD LAKGGRFKSN QEMAVYMQNL LNTSLIGGRA RVELLEKAFP
GNPIGIQIAS DDRQALTKAV NYIHDQLEAI PGTLNVEDDL DSAEYQFTVN VDNDKASQMG
ITKYDLERQM NIALKGAEST VFRKAGNEYP VVVTSDVNTK EALENLVIKS SLSFQEALLK
QLATIDLQAA IPTIRKYDRE QAITVSSQVK PGYSAVSIEE QLKQVIAENP DELKGVTLTY
KGEAKDIKDN FGDLGTAAIF ALFAIYLILM LQFRSFLQPF IIFITIPLSL FGVIIGLFAF
GQPLSFTALV GVVSLMGVVI KNAILLIEFI NHARKEGLSV HDACFDAVSK RYRPIFLSAM
TTVIGLVPLA LSGSDLFEPL SVAIMCGLTV STLLTLVIIP VVYSLWFSDH KAAVKEREGL
TV
//
