ID G7WPK0_METH6 Unreviewed; 594 AA.
AC G7WPK0;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Alkyl sulfatase {ECO:0000313|EMBL:AET65201.1};
GN OrderedLocusNames=Mhar_1844 {ECO:0000313|EMBL:AET65201.1};
OS Methanothrix harundinacea (strain 6Ac) (Methanosaeta harundinacea).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanotrichales; Methanotrichaceae; Methanothrix.
OX NCBI_TaxID=1110509 {ECO:0000313|EMBL:AET65201.1, ECO:0000313|Proteomes:UP000005877};
RN [1] {ECO:0000313|EMBL:AET65201.1, ECO:0000313|Proteomes:UP000005877}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=6Ac {ECO:0000313|EMBL:AET65201.1,
RC ECO:0000313|Proteomes:UP000005877};
RX PubMed=22590603; DOI=10.1371/journal.pone.0036756;
RA Zhu J., Zheng H., Ai G., Zhang G., Liu D., Liu X., Dong X.;
RT "The genome characteristics and predicted function of methyl-group
RT oxidation pathway in the obligate aceticlastic methanogens, Methanosaeta
RT spp.";
RL PLoS ONE 7:E36756-E36756(2012).
CC -!- SIMILARITY: Belongs to the metallo-beta-lactamase superfamily. Type III
CC sulfatase family. {ECO:0000256|ARBA:ARBA00033751}.
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DR EMBL; CP003117; AET65201.1; -; Genomic_DNA.
DR AlphaFoldDB; G7WPK0; -.
DR STRING; 1110509.Mhar_1844; -.
DR KEGG; mhi:Mhar_1844; -.
DR PATRIC; fig|1110509.7.peg.2043; -.
DR HOGENOM; CLU_014655_0_1_2; -.
DR Proteomes; UP000005877; Chromosome.
DR GO; GO:0018741; F:linear primary-alkylsulfatase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0018909; P:dodecyl sulfate metabolic process; IEA:InterPro.
DR CDD; cd07710; arylsulfatase_Sdsa1-like_MBL-fold; 1.
DR Gene3D; 1.25.40.880; Alkyl sulfatase, dimerisation domain; 1.
DR Gene3D; 3.60.15.30; Metallo-beta-lactamase domain; 1.
DR Gene3D; 3.30.1050.10; SCP2 sterol-binding domain; 1.
DR InterPro; IPR038536; Alkyl/aryl-sulf_dimr_sf.
DR InterPro; IPR029229; Alkyl_sulf_C.
DR InterPro; IPR029228; Alkyl_sulf_dimr.
DR InterPro; IPR044097; Bds1/SdsA1_MBL-fold.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR036527; SCP2_sterol-bd_dom_sf.
DR PANTHER; PTHR43223; ALKYL/ARYL-SULFATASE; 1.
DR PANTHER; PTHR43223:SF2; LACTAMASE_B DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF14864; Alkyl_sulf_C; 1.
DR Pfam; PF14863; Alkyl_sulf_dimr; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR SUPFAM; SSF55718; SCP-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000005877};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 73..292
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 594 AA; 65664 MW; CFD8343ECA162D07 CRC64;
MRRNITNGSK NMNAGKFFKA IILLLFFWLS SASAFEPEAV GANPDLVALN AGWFPPTVYD
VTDGVYVAVG YGRANPVLIE GTDGLIVIDP GESTTSAEMV KAAYNEHLDD IFSRKPVKAI
IYTHHHDCHI NGASVFAGND SPEVIAHETF EEHLFGPREV VSQIFPIKVY RAVKYAGIRF
QNDPGYFVNG GIFPFSVPGP SGYLPPTLTV GERLETNIAG VNLTIVHAPA ETTDINYVWL
PDKKVIVQIG IFYKSFPAIN TLRGASHRDP LNYIASIDDM RTLDAEYMVL IHSGGGPIVG
AENISQTLTN ARDALQYVHD QTVRLMNQGL TPGEIIEVLE LPPHLAEDPN LQEYFGEMDR
DIFQIFQQYM GWFTGRSRDI FPTSPREEAE KMAYLAGGVD GLAEKAKASL DEGDVKWAMI
FSDHVLLLDP ENVEAREVKN SSMLYLAEET KNAQVRNYIL SEYLEETGQI RIPIERGFSL
MDENIVVYMP MATIFRIMAV SLNATKALDE EYAVGLSLSD DSESAEYALY VRRGIVEVQE
GVPEDPKFTI DTDSLSMKNL VLGKLNPEEA VAGGAVEVGG AGPEEFYGFM DLFK
//
