ID   G7X773_ASPKW            Unreviewed;       577 AA.
AC   G7X773;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   RecName: Full=PNPLA domain-containing protein {ECO:0000259|PROSITE:PS51635};
GN   ORFNames=AKAW_01210 {ECO:0000313|EMBL:GAA83095.1};
OS   Aspergillus kawachii (strain NBRC 4308) (White koji mold) (Aspergillus
OS   awamori var. kawachi).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=1033177 {ECO:0000313|EMBL:GAA83095.1};
RN   [1] {ECO:0000313|EMBL:GAA83095.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IFO 4308 {ECO:0000313|EMBL:GAA83095.1};
RX   PubMed=22045919; DOI=10.1128/EC.05224-11;
RA   Futagami T., Mori K., Yamashita A., Wada S., Kajiwara Y., Takashita H.,
RA   Omori T., Takegawa K., Tashiro K., Kuhara S., Goto M.;
RT   "Genome sequence of the white koji mold Aspergillus kawachii IFO 4308, used
RT   for brewing the Japanese distilled spirit shochu.";
RL   Eukaryot. Cell 10:1586-1587(2011).
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DR   EMBL; DF126448; GAA83095.1; -; Genomic_DNA.
DR   AlphaFoldDB; G7X773; -.
DR   STRING; 1033177.G7X773; -.
DR   VEuPathDB; FungiDB:AKAW_01210; -.
DR   eggNOG; KOG4231; Eukaryota.
DR   InParanoid; G7X773; -.
DR   Proteomes; UP000006812; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0046486; P:glycerolipid metabolic process; IEA:UniProt.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd07216; Pat17_PNPLA8_PNPLA9_like3; 1.
DR   Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 1.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR   InterPro; IPR002641; PNPLA_dom.
DR   PANTHER; PTHR24185; CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA; 1.
DR   PANTHER; PTHR24185:SF1; CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA; 1.
DR   Pfam; PF01734; Patatin; 1.
DR   SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR   PROSITE; PS51635; PNPLA; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098}.
FT   DOMAIN          11..214
FT                   /note="PNPLA"
FT                   /evidence="ECO:0000259|PROSITE:PS51635"
SQ   SEQUENCE   577 AA;  65365 MW;  6500E04873E2EFFC CRC64;
     MSENKERLKI LALDGGGVKG LSSLLILERI MARVGAKMKR PDLQPYQYFD IIGGTSTGGI
     IALMLGRMRM TVESCIAEYQ KLGKIVFGEP RGLFHENMFD AKVLEEQTKK VVKKYLGDEN
     DPLLDPLGDD ACKTCSVVYT LPYRGATPEE PEALRTYINV NINPRPKPWT IWEAVRATSA
     ATTFFEPFIH GQSGSEIRYI DAGLGFNNPA DLVLEEATSL WTDNGYLDPE RDIGCFLTIG
     TGISSVTRMD KKTITEAITA KVRKPVQAVE VLMKIATGTG PTHRNVARRF NPTSNVYQRF
     DVDQGIQAFS LFEHERREDI EVDTNAYLGK HSIGVQLSQA VEKMKVLGLR TPELMEDRKE
     GGEVYSVGEN GDVDDQKLRD RFGALRISKL DFQRHAKHWE SKISVNQGRG SQYYYLLYKE
     IGHVPYLWNA FVQADLLDKR YRGILARRLP QADEWQLCLR GNLARIAYGV GQEDLETTVT
     RLTLAYEGLR DTFRIYRQLF HTAQQVFGET SVTYCWAAKR LGALLELWGC QSEALDLYIE
     ARAGKLSWFT TDHWSTKWLE NKIAALRHAL VARQKPE
//