ID G7XCY2_ASPKW Unreviewed; 1292 AA.
AC G7XCY2;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=DEAD/DEAH box RNA helicase {ECO:0000313|EMBL:GAA85072.1};
GN ORFNames=AKAW_03186 {ECO:0000313|EMBL:GAA85072.1};
OS Aspergillus kawachii (strain NBRC 4308) (White koji mold) (Aspergillus
OS awamori var. kawachi).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1033177 {ECO:0000313|EMBL:GAA85072.1};
RN [1] {ECO:0000313|EMBL:GAA85072.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IFO 4308 {ECO:0000313|EMBL:GAA85072.1};
RX PubMed=22045919; DOI=10.1128/EC.05224-11;
RA Futagami T., Mori K., Yamashita A., Wada S., Kajiwara Y., Takashita H.,
RA Omori T., Takegawa K., Tashiro K., Kuhara S., Goto M.;
RT "Genome sequence of the white koji mold Aspergillus kawachii IFO 4308, used
RT for brewing the Japanese distilled spirit shochu.";
RL Eukaryot. Cell 10:1586-1587(2011).
CC -!- SIMILARITY: Belongs to the helicase family. SKI2 subfamily.
CC {ECO:0000256|ARBA:ARBA00010140}.
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DR EMBL; DF126452; GAA85072.1; -; Genomic_DNA.
DR STRING; 1033177.G7XCY2; -.
DR VEuPathDB; FungiDB:AKAW_03186; -.
DR eggNOG; KOG0947; Eukaryota.
DR InParanoid; G7XCY2; -.
DR Proteomes; UP000006812; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR GO; GO:0006401; P:RNA catabolic process; IEA:InterPro.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.3380.30; -; 1.
DR Gene3D; 1.20.1500.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR048392; MTR4-like_stalk.
DR InterPro; IPR025696; MTR4_beta-barrel.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016438; SKI2-like.
DR InterPro; IPR012961; Ski2/MTR4_C.
DR InterPro; IPR040801; Ski2_N.
DR PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR PANTHER; PTHR12131:SF8; HELICASE SKI2W; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF08148; DSHCT; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF21408; MTR4-like_stalk; 1.
DR Pfam; PF13234; MTR4_beta-barrel; 1.
DR Pfam; PF17911; Ski2_N; 1.
DR PIRSF; PIRSF005198; Antiviral_helicase_SKI2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM01142; DSHCT; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:GAA85072.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 330..486
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 645..816
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 537..606
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 542..556
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1292 AA; 144294 MW; 6E4EFE3FE58BF00B CRC64;
MAETLTSALA ELSLNSQNLS ASAFDARLAE EEDGVYKDFK PRQKARQDAA DLKQELEQEF
LTPSSTFSPE WLNRLQRKWD VPTDYTDLFE VAGTQTRTIV RFDRDGLEGR VTGYHEVTVP
ATSANAKNST SLLRRPAGRA DFVRGAAGFF PFAPGGLDGV EAIAEMESEA QTPEHSRASG
KQSGLDRIIN FGAEGGLLEI APGFSRGLKF EEAKTKEAAE GDEEVEHALQ QEEADLHVEQ
EETASDAGGV KIDDEAELSD EEDIDSLLPV EFPALEPHAP LLAGMQQRKA GKEWAHVVDV
NKEIPNFRDL VPDMAREWPF ELDTFQKEAV YHLECGDSVF VAAHTSAGKT VVAEYAISLA
AKHMTKAIYT SPIKALSNQK FRDFRTEFDD VGILTGDVQI NPEASCLIMT TEILRSMLYR
GADLIRDVEF VIFDEVHYVN DLERGVVWEE VIIMLPEHVT LILLSATVPN TYEFASWVGR
TKKKDIYVIS TAKRPVPLEH YLWAGKGKYK IVDSNKRFLE NGWKEADEII SGRDKVKAQK
AAEAQAQSQA SRGGTPQGRG RGQAGGRGGA RGNGQRGGAP RGRGQPANRG TGNIARTGRG
GGRTTAAQDK TVWVQLVGHL RKENLLPGCI FVFSKKRCEQ NADSLSNQDF STASEKSLIH
MFIEKSLTRL KPEDRTLPQI LRLRELLSRG IAVHHGGLLP IMKEIVEILF AKSLVKVLFA
TETFAMGLNL PTRTVVFSGF RKHDGKGFRD LLPGEYTQMA GRAGRRGLDN VGYVIIVNAG
RDEAPPAGAL RRMILGDPTK LRSQFRLTYN MILNLLRVEA LKIEEMIKRS FSENATQALL
PEHEKQVQLS EASLAKIKRE PCDICDIDLA ACHAASIEYE KLTSELHVGL LSSPVGKRLF
VPKRLIVYRK EGFRTAGVIV REGVSGGQTP SIQVLEIGRL GHKRHPSDIL PFLPKFRHLL
QTLPTRAADM ALKAYKVPLL DLECVTNTIV KLGGPTWYLN IKKEASKFAD KELTKHCASW
TSPVWDEIDW ARIKELQVRD ILEKRQKQAS IAQGCKCLQC PSFLKHFEMQ HDEWQVKENI
TQLKQLMSDQ NLALLPDYEQ RIQVLKELGF VDEQSRVQLK GKVACEIHSA DELVLTELIL
ENVLAEYEPE EIVALLSAFV FQEKTENVPT LTPRLEKGKE AIVRISDRVN DFQIQHQVIQ
TSEDSNDFAS QPRFGLAEVV YEWAKGMSFN RITDLTDVME GTIVRTITRL DETCREVKNA
AKLVGDPTLY TKMQQAQEQI KRDVIFAASL YM
//
