ID G7XTN8_ASPKW Unreviewed; 399 AA.
AC G7XTN8;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=O-methyltransferase {ECO:0000313|EMBL:GAA90297.1};
GN ORFNames=AKAW_08411 {ECO:0000313|EMBL:GAA90297.1};
OS Aspergillus kawachii (strain NBRC 4308) (White koji mold) (Aspergillus
OS awamori var. kawachi).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1033177 {ECO:0000313|EMBL:GAA90297.1};
RN [1] {ECO:0000313|EMBL:GAA90297.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IFO 4308 {ECO:0000313|EMBL:GAA90297.1};
RX PubMed=22045919; DOI=10.1128/EC.05224-11;
RA Futagami T., Mori K., Yamashita A., Wada S., Kajiwara Y., Takashita H.,
RA Omori T., Takegawa K., Tashiro K., Kuhara S., Goto M.;
RT "Genome sequence of the white koji mold Aspergillus kawachii IFO 4308, used
RT for brewing the Japanese distilled spirit shochu.";
RL Eukaryot. Cell 10:1586-1587(2011).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DF126472; GAA90297.1; -; Genomic_DNA.
DR AlphaFoldDB; G7XTN8; -.
DR VEuPathDB; FungiDB:AKAW_08411; -.
DR eggNOG; KOG3178; Eukaryota.
DR InParanoid; G7XTN8; -.
DR Proteomes; UP000006812; Unassembled WGS sequence.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43712:SF11; O-METHYLTRANSFERASE (AFU_ORTHOLOGUE AFUA_2G17820)-RELATED; 1.
DR PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:GAA90297.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:GAA90297.1}.
FT DOMAIN 171..376
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 305
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 399 AA; 44580 MW; 5E312DF4A31EDE2A CRC64;
MADTVNALTS AVNSTLAKLT PGDEIAEADR YQLLDAIDKL RVAVEPPLLT VRNLCFGHHG
LVAIRVAMGM GIFDAFASAK NGEMNADALD ENTKGDKALL VRIMRVLCAN HVFEETGVEK
YRALPLAIMF ASNNPPSEVI KHFHSDMKAS VHSYDYFEAR GYRNPQDAYD TTFQLAFGTK
EHYFEWIQHN PEELHAFNTV MEIGNRSLEG VQWYDYYPWQ ENLATTDNTN RVLLVDIGGG
KGHDLSGFKR KFPEVKNPLI VQDLPGVIGD IQEPLIQGVN AVGHNMFDPQ PVKGAKAYYM
RTVLHDWPDK QALHALGHLH DAMAADSVLL INENVLPEMN ASGFSASMDI IMMELYGSLE
RTEKQWLELL EKAKFRVVKV WRSGFQGTGS NALFEAVPV
//
