ID G7XYH1_ASPKW Unreviewed; 1008 AA.
AC G7XYH1;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Pantothenate transporter {ECO:0000313|EMBL:GAA91967.1};
GN ORFNames=AKAW_10081 {ECO:0000313|EMBL:GAA91967.1};
OS Aspergillus kawachii (strain NBRC 4308) (White koji mold) (Aspergillus
OS awamori var. kawachi).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1033177 {ECO:0000313|EMBL:GAA91967.1};
RN [1] {ECO:0000313|EMBL:GAA91967.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IFO 4308 {ECO:0000313|EMBL:GAA91967.1};
RX PubMed=22045919; DOI=10.1128/EC.05224-11;
RA Futagami T., Mori K., Yamashita A., Wada S., Kajiwara Y., Takashita H.,
RA Omori T., Takegawa K., Tashiro K., Kuhara S., Goto M.;
RT "Genome sequence of the white koji mold Aspergillus kawachii IFO 4308, used
RT for brewing the Japanese distilled spirit shochu.";
RL Eukaryot. Cell 10:1586-1587(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DF126486; GAA91967.1; -; Genomic_DNA.
DR AlphaFoldDB; G7XYH1; -.
DR STRING; 1033177.G7XYH1; -.
DR VEuPathDB; FungiDB:AKAW_10081; -.
DR eggNOG; KOG1399; Eukaryota.
DR eggNOG; KOG2533; Eukaryota.
DR InParanoid; G7XYH1; -.
DR Proteomes; UP000006812; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0004499; F:N,N-dimethylaniline monooxygenase activity; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR020946; Flavin_mOase-like.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR43791; PERMEASE-RELATED; 1.
DR PANTHER; PTHR43791:SF39; TRANSPORTER LIZ1_SEO1, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00980)-RELATED; 1.
DR Pfam; PF00743; FMO-like; 2.
DR Pfam; PF07690; MFS_1; 1.
DR Pfam; PF13450; NAD_binding_8; 1.
DR PRINTS; PR00419; ADXRDTASE.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 613..630
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 636..653
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 674..696
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 708..728
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 775..797
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 848..868
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 940..960
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 547..1008
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 55..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 974..1002
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 980..1002
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1008 AA; 112657 MW; 731918F5EC05CF00 CRC64;
MTREIQQVAV IGAGISGVVS AAHLLAHGID VTVFERNHAA GGVWLHDERK PLEPNYPAMK
PSISERHRDE DRRHADVLSL EHAPPGPCYD GLKNNVATSL MRVKLNAWPE GTPEFVSHTV
MKEYIQDTSK KAGAESVTLY GARVTRLRKV DRKWDVTWST LKETTQSGTL EEQEETAKFD
AVIVASGHYH APRVPDTPGL SKAKAQWPSR ITHSKGYRNP NPYAGKNVLL IGGGVSSTDL
AREIGPLAKK VYQSTRNGEF DISSSVLPEN GTRVSEIERF EIAAKTAADD EALPIKVHLK
SGQTLCGIDA IIICTGYHIT LPFLSEYHDD ATPAEKASDT VLVTDGTQVH NLHKDIFYIP
DPTLAFVGVP YYTATFTLFE FQAIAVANVF AGIAELPAES EMKDEYARRV KEKGSGKRFH
SLKDIEEFYV IDLLEWINGY RAKYGLTAIE AHSDNWHLAK AAQRERTNKL LGLGRRRDSG
IGELPVLEIK TGIIMAPSPA TVEERAVDTS SGIVQANPKR RWVSYIWDTF DKSPEERRLL
FKLDSAILTF ASLGYFIKYL DQININNAFV SGMKEDLGLY GNQLNYMQAC WTVGYVIGEI
PSNMLLTRIR PRYWIPAMEL LWTVLTFALS RSTSATHFYV LRFFIGLAES SFYPGMQYII
GSWYRKDELA KRSCIFHTSS GIASMFSGYL MDAVFHLGGR GGLKGWQWLF LIDGIISIPV
AISGFFILPD VPEISSPFYL SEQEVKLAQK RMQFEGRKDR EPYTKSKLKK IFSSWHIYLL
TIVYITFNNG AAGSQPVFQQ YLKDSTNPVY SVGQINAYPT TTNAVQVVTT LIYAWTSDTI
LQGRRWPCII IGACINIICY VSLAVWNIPT GWKWTCYILS GAGYGLSGLC MAWAHEICTD
DNEERALVVG SMNEMAYVFQ AWLPLVVWQQ VDAPRYRKGF ITVTIMSVIL IISTVVTWRL
QVWEGKRPKN VQAEVVDGGG RSESEGDDSS RDDGRVEGVV DGGLVRKV
//
