ID G7Y4T5_CLOSI Unreviewed; 1633 AA.
AC G7Y4T5;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=26S proteasome regulatory subunit N2 {ECO:0000313|EMBL:GAA47971.1};
GN ORFNames=CLF_101028 {ECO:0000313|EMBL:GAA47971.1};
OS Clonorchis sinensis (Chinese liver fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Clonorchis.
OX NCBI_TaxID=79923 {ECO:0000313|EMBL:GAA47971.1, ECO:0000313|Proteomes:UP000008909};
RN [1] {ECO:0000313|EMBL:GAA47971.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Henan {ECO:0000313|EMBL:GAA47971.1};
RX PubMed=22023798; DOI=10.1186/gb-2011-12-10-r107;
RA Wang X., Chen W., Huang Y., Sun J., Men J., Liu H., Luo F., Guo L., Lv X.,
RA Deng C., Zhou C., Fan Y., Li X., Huang L., Hu Y., Liang C., Hu X., Xu J.,
RA Yu X.;
RT "The draft genome of the carcinogenic human liver fluke Clonorchis
RT sinensis.";
RL Genome Biol. 12:R107-R107(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Henan;
RA Wang X., Huang Y., Chen W., Liu H., Guo L., Chen Y., Luo F., Zhou W.,
RA Sun J., Mao Q., Liang P., Zhou C., Tian Y., Men J., Lv X., Huang L.,
RA Zhou J., Hu Y., Li R., Zhang F., Lei H., Li X., Hu X., Liang C., Xu J.,
RA Wu Z., Yu X.;
RT "The genome and transcriptome sequence of Clonorchis sinensis provide
RT insights into the carcinogenic liver fluke.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DF142863; GAA47971.1; -; Genomic_DNA.
DR Proteomes; UP000008909; Unassembled WGS sequence.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR002015; Proteasome/cyclosome_rpt.
DR InterPro; IPR048570; PSMD1_RPN2_N.
DR InterPro; IPR040623; RPN2_C.
DR PANTHER; PTHR10943; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR10943:SF2; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 1; 1.
DR Pfam; PF13646; HEAT_2; 1.
DR Pfam; PF01851; PC_rep; 2.
DR Pfam; PF18004; RPN2_C; 1.
DR Pfam; PF21505; RPN2_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 4: Predicted;
KW Proteasome {ECO:0000256|ARBA:ARBA00022942, ECO:0000313|EMBL:GAA47971.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008909};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 500..775
FT /note="26S proteasome non-ATPase regulatory subunit 1/RPN2
FT N-terminal"
FT /evidence="ECO:0000259|Pfam:PF21505"
FT DOMAIN 1320..1475
FT /note="26S proteasome regulatory subunit RPN2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18004"
FT REGION 786..844
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1340..1421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1507..1633
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 791..806
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 807..823
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1352..1421
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1549..1563
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1579..1594
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1599..1633
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1633 AA; 179912 MW; AB37268611A8ACB7 CRC64;
MIENAHSYEY ERPSLAENSV TFYTVRVPAC VLPSTHSSKD LLCPTPKQRH RNRRDRGPEK
MNAVTVSYIY VEKQNGLPNT VIYEGILSSN HIFQTQIAGD FFTYSCNSFY VNDLPDVLSS
PCLLFADDLK SWSSNASAPQ IDVDAAKQWS LDWHLPLNDE ECVHMSFGGD SANSFVMHGE
KGPEDITRID AKKDLGIWLS PNLSFSLHLE KSAQKAFAVL RMIRCTLSHI TRTDFQILCG
AYVRPLLEYA NPVVYPGRTK DVILIERAQR ATTKWLPVSS PWTTKRISWF LTYFPPGYRR
LRGDLILTYA LFEQGLANRF FTVDPANTRR GHAAQEDCSG CKRSKLERSS GVGSYELEGI
EGKCLRIQRT TFADVADNDA EAAICNGFIP RAAQSSTTAS AGVPFKRSVS SESNVRASSP
TPWLFNYHTK LSPDSIPDVP CQRAFGIFSC ENLQQLLYPM QTSGRSRLKF ISRAKLAAST
SGYASHHQPQ PSRPGSRPLA YALKRLDELV DEFWAEISES VSKIEILHED IGFEHNKLAA
LLASKVYYHL AEYEDALHFA LCAEELFDPN TQSEFVETIV AKCIDKYTEL RVARDQMLDS
GSSLPRQDST GDRTWSSSSA TYKRLELVVD RMFDRCFEHK QYKQALGIAI ETRRLDIFEK
ALTLAPDREG MLRYAFRVVL TLIDSARLRN RLLRIIVSVF MSRPSPTDAI NVCQCLVLID
DPQATADTLE RLLLQSAEGA VTAYQIGFDL YENSAQMFLH RVSAALARSA KLSNIFNAID
KEKHKDQKTA PIIESSSAGS TAEATKTTDD QPEKKETQEG EDSAAAETKP TAPTAPPVVV
EPLSETDKEI KKRVENLMSI LSGDKVIELH LQFLIRNNKA DLRLLERIRE EVRHSVTHNA
TVLANGIMHC GTTSDQFLRD HLSWLGKAVN WAKFTATATL GVIHRGHEKE ALRLMSAYLP
KDASGSSGSV YTEGGGLFAL GLIHANHGGT MTEYLLNQCK EAIAEPVRHG ACLGLGLAAM
STGREDVYDQ MKLNLYQDDA VTGEAAAIGI GLVMLGTGST QAIEDLLGYA KETAHEKIIR
GIALGIAMVM YGRAQEADEL IDRLAVDNDP ILRWSGMATV AMAYCGTGNN KAVQRLLHSA
VSDTNDDVRR WAVTALGFVM FKTPEQVPAL VSLLTESYHP HLRYGAAMAM GVACAGTALK
EATTLLDTLC EGTVPFVRQG ALIASAMVLM QQNAITCPKS VEFREKCLKI IGDRHEDLLA
KFGAILACGI LDAGGCNMTI SLQTRTGNNN MTAAVGLLLF QNFWFWYPLT NFLSLALSPT
TLIALNKDLK MPKMQFKSNA KPSTFAYPQP LQPEKEKKRE KVETAVLSIT AKQRKKEADR
KHHKEQQQQQ KPKDGEKEEK MDVDAPAKDE KPVEEKKEDK EPNFLMLNNP ARVMRVQQRV
MALPESSRYH TLKPITQAGI LMVHDRRPQD AEVLVEIVHG HGPTGDRNIT SASVAGTTGV
AGLPAAGAVG SEAPAQGVTE KTDVEMSGAA GATPSSGTKR DKSKTSGSAR HGKTGSSSNV
EPSPPEPFLY VEEGTEPAAT AVTPTTSTSA TVAPKEAPSH EPMEVEEEPS EGGVGSNKKD
KEDKSEKRDD VKK
//
