ID G7YLK4_CLOSI Unreviewed; 405 AA.
AC G7YLK4;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=AP-3 complex subunit mu {ECO:0000256|ARBA:ARBA00040763};
DE AltName: Full=Adaptor-related protein complex 3 subunit mu {ECO:0000256|ARBA:ARBA00043093};
DE Flags: Fragment;
GN ORFNames=CLF_111261 {ECO:0000313|EMBL:GAA53835.1};
OS Clonorchis sinensis (Chinese liver fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Clonorchis.
OX NCBI_TaxID=79923 {ECO:0000313|EMBL:GAA53835.1, ECO:0000313|Proteomes:UP000008909};
RN [1] {ECO:0000313|EMBL:GAA53835.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Henan {ECO:0000313|EMBL:GAA53835.1};
RX PubMed=22023798; DOI=10.1186/gb-2011-12-10-r107;
RA Wang X., Chen W., Huang Y., Sun J., Men J., Liu H., Luo F., Guo L., Lv X.,
RA Deng C., Zhou C., Fan Y., Li X., Huang L., Hu Y., Liang C., Hu X., Xu J.,
RA Yu X.;
RT "The draft genome of the carcinogenic human liver fluke Clonorchis
RT sinensis.";
RL Genome Biol. 12:R107-R107(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Henan;
RA Wang X., Huang Y., Chen W., Liu H., Guo L., Chen Y., Luo F., Zhou W.,
RA Sun J., Mao Q., Liang P., Zhou C., Tian Y., Men J., Lv X., Huang L.,
RA Zhou J., Hu Y., Li R., Zhang F., Lei H., Li X., Hu X., Liang C., Xu J.,
RA Wu Z., Yu X.;
RT "The genome and transcriptome sequence of Clonorchis sinensis provide
RT insights into the carcinogenic liver fluke.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the adaptor complexes medium subunit family.
CC {ECO:0000256|ARBA:ARBA00005324}.
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DR EMBL; DF143608; GAA53835.1; -; Genomic_DNA.
DR AlphaFoldDB; G7YLK4; -.
DR Proteomes; UP000008909; Unassembled WGS sequence.
DR GO; GO:0030131; C:clathrin adaptor complex; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd09252; AP-3_Mu3_Cterm; 1.
DR CDD; cd14837; AP3_Mu_N; 1.
DR Gene3D; 3.30.450.60; -; 1.
DR Gene3D; 2.60.40.1170; Mu homology domain, subdomain B; 2.
DR InterPro; IPR036168; AP2_Mu_C_sf.
DR InterPro; IPR022775; AP_mu_sigma_su.
DR InterPro; IPR001392; Clathrin_mu.
DR InterPro; IPR018240; Clathrin_mu_CS.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR InterPro; IPR028565; MHD.
DR PANTHER; PTHR10529; AP COMPLEX SUBUNIT MU; 1.
DR PANTHER; PTHR10529:SF340; CARMINE, ISOFORM A; 1.
DR Pfam; PF00928; Adap_comp_sub; 1.
DR Pfam; PF01217; Clat_adaptor_s; 1.
DR PIRSF; PIRSF005992; Clathrin_mu; 1.
DR PRINTS; PR00314; CLATHRINADPT.
DR SUPFAM; SSF49447; Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor; 1.
DR SUPFAM; SSF64356; SNARE-like; 1.
DR PROSITE; PS00991; CLAT_ADAPTOR_M_2; 1.
DR PROSITE; PS51072; MHD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000008909};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 165..404
FT /note="MHD"
FT /evidence="ECO:0000259|PROSITE:PS51072"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:GAA53835.1"
SQ SEQUENCE 405 AA; 45033 MW; 60AA8ABEF84A69D9 CRC64;
EICLEKHWSK VTPKAVCDQF FEAVSQSTSV DEIPIVIESN KECLIHISKG RLFFVAVCVD
EVPPLLVIEL LLSLANVIVD YFGTVNESVI KDNLVCIYEI LDEMIDGGFP LATEPNVLKD
IVRPANILKT ITDVVTGTNS AVSSTLPSCQ LSNVRWRRGH VKHTNNEVYF DLIEQVNAIV
DSSGNTVFKE VDGSIECFSK LSGVPDLTLA FSNNRLIDDA SLHPCIRLLR WERERVLSFI
PPDGRFCLFR YHVNCLSPLT LPVIVRHSIS LREQGSRLDL VVIPKTLGRT MESVRLTMHM
PSSVVNVNAT PSTGRVMFDT TTRLFEWNIG RIDSKHANPT LKGSVTLSPG VSATPGNPSI
MVHFSVPQYA VSGLKIARVD IYAEKYKPFK GVKYLTSSGK FEVRT
//
