ID G7YYV1_CLOSI Unreviewed; 780 AA.
AC G7YYV1;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 28-JUN-2023, entry version 44.
DE SubName: Full=SH3 and multiple ankyrin repeat domains protein 3 {ECO:0000313|EMBL:GAA58130.1};
GN ORFNames=CLF_113598 {ECO:0000313|EMBL:GAA58130.1};
OS Clonorchis sinensis (Chinese liver fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Clonorchis.
OX NCBI_TaxID=79923 {ECO:0000313|EMBL:GAA58130.1, ECO:0000313|Proteomes:UP000008909};
RN [1] {ECO:0000313|EMBL:GAA58130.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Henan {ECO:0000313|EMBL:GAA58130.1};
RX PubMed=22023798; DOI=10.1186/gb-2011-12-10-r107;
RA Wang X., Chen W., Huang Y., Sun J., Men J., Liu H., Luo F., Guo L., Lv X.,
RA Deng C., Zhou C., Fan Y., Li X., Huang L., Hu Y., Liang C., Hu X., Xu J.,
RA Yu X.;
RT "The draft genome of the carcinogenic human liver fluke Clonorchis
RT sinensis.";
RL Genome Biol. 12:R107-R107(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Henan;
RA Wang X., Huang Y., Chen W., Liu H., Guo L., Chen Y., Luo F., Zhou W.,
RA Sun J., Mao Q., Liang P., Zhou C., Tian Y., Men J., Lv X., Huang L.,
RA Zhou J., Hu Y., Li R., Zhang F., Lei H., Li X., Hu X., Liang C., Xu J.,
RA Wu Z., Yu X.;
RT "The genome and transcriptome sequence of Clonorchis sinensis provide
RT insights into the carcinogenic liver fluke.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DF145374; GAA58130.1; -; Genomic_DNA.
DR AlphaFoldDB; G7YYV1; -.
DR Proteomes; UP000008909; Unassembled WGS sequence.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR24135:SF28; LD13733P; 1.
DR PANTHER; PTHR24135; SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00248; ANK; 5.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000008909}.
FT REPEAT 231..263
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 331..363
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 490..580
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 677..700
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 780 AA; 86943 MW; E66D2915B5910BD2 CRC64;
MGLPSEDPDS QLACQYSIDS FLSPTSSDSL MGQVNKTLIE IIIPDHEWKF VYRVPTDTLV
RELLRRIFTT CRLDVVEYAN YGLYMPPQGV QKGKFLQEER PLCEYPQLMP QLGTASENRQ
SNGEQGCQNC TEPSGTLKLI KKSRYVDGIP MSTHKFRYIN SKSHQKQFLS AIRERNIRRM
DDMLDRGLDP NFQYSSTGET PLCCATLQLF SKDLILKLVE KGALLEFRDD DGFTPLHRAA
ICGNLESIKV LLDLGMNPNV RDGKSLTPLY YAVSRDIPTK CIALLLYDHA ILGVVDDKNR
QEIHQACLFD KPGHLEQLII YGADLDAQTS NLDTALHICA LNNHETCLRL LLKYGATRDM
VNASGQTPSE VALLTGLRKL AELIDNFPDE EIVRTSRTPI YNTDRRPTAG GPRAALEAHR
ARHNFGDLPN SLDRLSSLGL SPNPRSMSNF TSSMGSVEVR YADGSILGLN NGGQHSSHTE
NGNNRVRTRQ ITLFRGNSGF GFQIRGPRDS LDSRRSSSVP ANQYIDEIFP NTPAARAGLK
AGDYLLEVNG ENVRDACHQH VASLIAGSGP RVTLKVVGGA TNGAPPRRRI QMIDRRQSNY
VRPQYSTEFR RSSSHDQAYI TAYCPPITLS LSRPYEYRKP SPANADYEAL ASMNTGDYSP
TLTREICIRT LTRSRNSSSS TVNSLTDAES DVSFSNGQAS STASTKEDFL FTPHVKVLRE
NNSIPLSKVT ISREMDENRI SHPRTTDKIR FASGSLDEEV PLYDFVDFTS TEEQSDAPTE
//
