ID G7ZF97_AZOL4 Unreviewed; 394 AA.
AC G7ZF97;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Putative multidrug efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:CBS90141.1};
GN OrderedLocusNames=AZOLI_p30309 {ECO:0000313|EMBL:CBS90141.1};
OS Azospirillum lipoferum (strain 4B).
OG Plasmid AZO_p3 {ECO:0000313|EMBL:CBS90141.1,
OG ECO:0000313|Proteomes:UP000005667}.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Azospirillaceae; Azospirillum.
OX NCBI_TaxID=862719 {ECO:0000313|EMBL:CBS90141.1, ECO:0000313|Proteomes:UP000005667};
RN [1] {ECO:0000313|Proteomes:UP000005667}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=4B {ECO:0000313|Proteomes:UP000005667};
RC PLASMID=Plasmid AZO_p3 {ECO:0000313|Proteomes:UP000005667};
RX PubMed=22216014; DOI=10.1371/journal.pgen.1002430;
RA Wisniewski-Dye F., Borziak K., Khalsa-Moyers G., Alexandre G.,
RA Sukharnikov L.O., Wuichet K., Hurst G.B., McDonald W.H., Robertson J.S.,
RA Barbe V., Calteau A., Rouy Z., Mangenot S., Prigent-Combaret C.,
RA Normand P., Boyer M., Siguier P., Dessaux Y., Elmerich C., Condemine G.,
RA Krishnen G., Kennedy I., Paterson A.H., Gonzalez V., Mavingui P.,
RA Zhulin I.B.;
RT "Azospirillum genomes reveal transition of bacteria from aquatic to
RT terrestrial environments.";
RL PLoS Genet. 7:E1002430-E1002430(2011).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; FQ311871; CBS90141.1; -; Genomic_DNA.
DR RefSeq; WP_014249582.1; NC_016623.1.
DR AlphaFoldDB; G7ZF97; -.
DR KEGG; ali:AZOLI_p30309; -.
DR HOGENOM; CLU_018816_2_1_5; -.
DR OrthoDB; 9816569at2; -.
DR Proteomes; UP000005667; Plasmid AZO_p3.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30158; ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER; 1.
DR PANTHER; PTHR30158:SF10; HLYD FAMILY SECRETION PROTEIN; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Plasmid {ECO:0000313|EMBL:CBS90141.1}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..394
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003507034"
FT DOMAIN 72..294
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 368..394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 394 AA; 41341 MW; AA9E22C695E2E1C8 CRC64;
MTKSRSKLAL LLIAGVAAAG AAGIVVSQGH ADAPQTAAAA PPPPEVDVAP VVVRKITDWQ
SYSGRLEAVE RVDVRPQVAG AITAVHFRNG ALVRQGDVLF TIDPRPFAAE VARQEAQVAA
AQARVRFTAA DLERAQRLVR DDTISRQSLE SKENEARSAA ANLKAAQAAL EIARIDLEHS
QVRAPVSGRV SRAEVTVGNV VAAGAAAAPL TTLVSVSPIY ASFDVDEQTY LTHIAGVKDA
SGVPVQLGLA NEDGYSRDGA VEHVDNRMDA ASGTIRVRAR FDNADGLLVP GLYARIKVGG
SKPHDALMVD DRAIGTDQDK KFVLVVAEDG TVTYRAIVTG AHQAGLRVVK SGLEPGERIV
VNGLQHARPG SRVSPRTVAM NGTPEPIRTA STAP
//
