ID G8B6J0_CANPC Unreviewed; 460 AA.
AC G8B6J0;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=B30.2/SPRY domain-containing protein {ECO:0000259|PROSITE:PS50188};
GN OrderedLocusNames=CPAR2_101100 {ECO:0000313|CGD:CAL0000148685,
GN ECO:0000313|EMBL:CCE40072.1};
OS Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia
OS parapsilosis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=578454 {ECO:0000313|EMBL:CCE40072.1, ECO:0000313|Proteomes:UP000005221};
RN [1] {ECO:0000313|Proteomes:UP000005221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 317 / ATCC MYA-4646 {ECO:0000313|Proteomes:UP000005221};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
RN [2] {ECO:0000313|Proteomes:UP000005221}
RP GENOME REANNOTATION.
RC STRAIN=CDC 317 / ATCC MYA-4646 {ECO:0000313|Proteomes:UP000005221};
RX PubMed=22192698; DOI=10.1186/1471-2164-12-628;
RA Guida A., Lindstaedt C., Maguire S.L., Ding C., Higgins D.G., Corton N.J.,
RA Berriman M., Butler G.;
RT "Using RNA-seq to determine the transcriptional landscape and the hypoxic
RT response of the pathogenic yeast Candida parapsilosis.";
RL BMC Genomics 12:628-628(2011).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the cclA family.
CC {ECO:0000256|ARBA:ARBA00038149}.
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DR EMBL; HE605203; CCE40072.1; -; Genomic_DNA.
DR AlphaFoldDB; G8B6J0; -.
DR STRING; 578454.G8B6J0; -.
DR EnsemblFungi; CPAR2_101100-T; CPAR2_101100-T-p1; CPAR2_101100.
DR CGD; CAL0000148685; CPAR2_101100.
DR VEuPathDB; FungiDB:CPAR2_101100; -.
DR eggNOG; KOG2626; Eukaryota.
DR Proteomes; UP000005221; Chromosome 1.
DR GO; GO:0048188; C:Set1C/COMPASS complex; IEA:InterPro.
DR CDD; cd12872; SPRY_Ash2; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR InterPro; IPR037353; ASH2.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR10598; SET1/ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2; 1.
DR PANTHER; PTHR10598:SF0; SET1_ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2; 1.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000005221}.
FT DOMAIN 102..293
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 460 AA; 53057 MW; 1A8CCF18AD4522E0 CRC64;
MRQGFSEEPS IEPQVQAIGD DGGGMTRRDE SHLTAQQPSI TIQEQHNVII QPRLRPMPFK
LQDISQPSLP IPTEVCTLNG ETYYQVEDLP VNRRGFKYKL CRPNPLFTSN FYATTDLPPY
QACISLFDRA PAMLFSKDSM SVTQAKGWRS ARSNVGVREG SYYFEFKILN SDKNSHVRVG
VARREASLEA PVGYDAYGYG IRDVDGQLMF ISRRKNVCVE NGFTTGDVIG FLVQLPSLKE
HKREIEEFVE NKRAEMSMEH KSKKRKHKWK QISVEENEMF IAHDNIVRDQ IPTKSKGALY
YDQYEYTRTK TMDHLLNPIT VFGEKAVIEM DDKTKNIPVI TNSKIRVFKN GIEQDTCIDN
LYSFLPTNIE TREDLNLEPN VQQSQNPGYR NTDDNTLGYY PMLSTFQNGA VRLNAGPEFD
FPPPETVKPL NDRYEEQVIE EWYWDILDEV EAQYLDNFDD
//
