ID G8BB87_CANPC Unreviewed; 516 AA.
AC G8BB87;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Transcription initiation factor TFIID subunit 12 {ECO:0000256|ARBA:ARBA00017484};
GN OrderedLocusNames=CPAR2_808600 {ECO:0000313|CGD:CAL0000156555,
GN ECO:0000313|EMBL:CCE42311.1};
OS Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia
OS parapsilosis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=578454 {ECO:0000313|EMBL:CCE42311.1, ECO:0000313|Proteomes:UP000005221};
RN [1] {ECO:0000313|Proteomes:UP000005221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 317 / ATCC MYA-4646 {ECO:0000313|Proteomes:UP000005221};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
RN [2] {ECO:0000313|Proteomes:UP000005221}
RP GENOME REANNOTATION.
RC STRAIN=CDC 317 / ATCC MYA-4646 {ECO:0000313|Proteomes:UP000005221};
RX PubMed=22192698; DOI=10.1186/1471-2164-12-628;
RA Guida A., Lindstaedt C., Maguire S.L., Ding C., Higgins D.G., Corton N.J.,
RA Berriman M., Butler G.;
RT "Using RNA-seq to determine the transcriptional landscape and the hypoxic
RT response of the pathogenic yeast Candida parapsilosis.";
RL BMC Genomics 12:628-628(2011).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TAF12 family.
CC {ECO:0000256|ARBA:ARBA00007530}.
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DR EMBL; HE605205; CCE42311.1; -; Genomic_DNA.
DR AlphaFoldDB; G8BB87; -.
DR STRING; 578454.G8BB87; -.
DR EnsemblFungi; CPAR2_808600-T; CPAR2_808600-T-p1; CPAR2_808600.
DR CGD; CAL0000156555; CPAR2_808600.
DR VEuPathDB; FungiDB:CPAR2_808600; -.
DR eggNOG; KOG1142; Eukaryota.
DR Proteomes; UP000005221; Chromosome 8.
DR GO; GO:0000124; C:SAGA complex; IEA:InterPro.
DR GO; GO:0046695; C:SLIK (SAGA-like) complex; IEA:InterPro.
DR GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR CDD; cd07981; TAF12; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR037794; TAF12.
DR InterPro; IPR003228; TFIID_TAF12_dom.
DR PANTHER; PTHR12264; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12; 1.
DR PANTHER; PTHR12264:SF21; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12; 1.
DR Pfam; PF03847; TFIID_20kDa; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000005221};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 420..491
FT /note="Transcription initiation factor TFIID subunit 12"
FT /evidence="ECO:0000259|Pfam:PF03847"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 68..161
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 237..393
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 81..161
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 516 AA; 55642 MW; 47E1C45F2AA04CE7 CRC64;
MEGSSNQSIT KNTTPTPEAE LNPQRVKALL NKLHEEFNAS KTETDPIKVK EHLAKVDKIK
RVLKIYHDQQ KQRQGGDLAH VASGNAQSQQ TSHQPAISTQ SGTDPSVAMT AAATSSVQSP
LVNLQPSSHS QAHAPPQDNV TSQFPQIQSP APQRPNSASP DAQKITVEKY NQVKSVLKDL
AEKVQSLTSA KERETDPTRI QAMEKTLTES RVQLQQYHKG ALYMRKVLMD SGRLAANATP
VSSPRPVTAA TTATTTATTA ATTATTTAAP PIASDISSAT THQQNSSIER ITSPAPPKIS
NADQQSSSHP KSTLPQAIPN SSAITVNKKL PSPISNESKP TPSPTSTKPP AVTKTSSATK
APTAISQPST ANTTTTTKRP QISTNPTTTS STNLVNSLRA FGNSPTVSTS IPDNDGRVLT
KRKLNELITN LSIDQGDTKP SVDNDVEELF LDLADEFVRS VMGFSCNLAK HRKLDKLDIR
DVSLNLERNW GIKVPGYMPD EIKPARRWPK KPDHKN
//
