ID G8BGH2_CANPC Unreviewed; 800 AA.
AC G8BGH2;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=AB hydrolase-1 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=CPAR2_205980 {ECO:0000313|CGD:CAL0000156801,
GN ECO:0000313|EMBL:CCE42956.1};
OS Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia
OS parapsilosis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=578454 {ECO:0000313|EMBL:CCE42956.1, ECO:0000313|Proteomes:UP000005221};
RN [1] {ECO:0000313|Proteomes:UP000005221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 317 / ATCC MYA-4646 {ECO:0000313|Proteomes:UP000005221};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
RN [2] {ECO:0000313|Proteomes:UP000005221}
RP GENOME REANNOTATION.
RC STRAIN=CDC 317 / ATCC MYA-4646 {ECO:0000313|Proteomes:UP000005221};
RX PubMed=22192698; DOI=10.1186/1471-2164-12-628;
RA Guida A., Lindstaedt C., Maguire S.L., Ding C., Higgins D.G., Corton N.J.,
RA Berriman M., Butler G.;
RT "Using RNA-seq to determine the transcriptional landscape and the hypoxic
RT response of the pathogenic yeast Candida parapsilosis.";
RL BMC Genomics 12:628-628(2011).
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DR EMBL; HE605206; CCE42956.1; -; Genomic_DNA.
DR AlphaFoldDB; G8BGH2; -.
DR EnsemblFungi; CPAR2_205980-T; CPAR2_205980-T-p1; CPAR2_205980.
DR CGD; CAL0000156801; CPAR2_205980.
DR VEuPathDB; FungiDB:CPAR2_205980; -.
DR eggNOG; ENOG502QVNJ; Eukaryota.
DR Proteomes; UP000005221; Chromosome 2.
DR GO; GO:0008374; F:O-acyltransferase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR003386; LACT/PDAT_acylTrfase.
DR PANTHER; PTHR11440:SF97; BCDNA.GH02384; 1.
DR PANTHER; PTHR11440; LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED; 1.
DR Pfam; PF02450; LCAT; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005221}.
FT REGION 1..133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 529..567
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 588..647
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..28
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..66
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 77..117
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 540..567
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 800 AA; 89219 MW; 6EF961B52EFFDC12 CRC64;
MVSTRESPLS SPPKSPSDQL SFLSPQPTLD AHAGTDYQAK LLNREEISDD EDSMDSEEEE
DDGAEANGGA ENINIHSYDA INANGKHNGG ASSVNSNDNE DQVREYNPVS ATHTLSRRLT
KSDAESLVGG DSIKDVHDEY EADKNRAHPT ADPDQPTEDQ EVKIGDHTFT DNKMKQYNPQ
QKVFSFSLPF GGGFSSLREN LTRHLSSLKK IDVPFVGHEN DHKIDEELHR KVEQRLQRQQ
SISTIDEENY FKGFKGVDGG RSEAVRHAIT SNLTELIPHK NKKELADYET IYDRIDGNIV
IMGGYRGSIL RDAKTHKRVW IPLKAGFNLR KINLLLGPNK EDELNAEDKI YPDGILSHIG
PIDICRKLIK KLDANPKVNM QEFGYDWRLS GDYVSQKLER FLAKIYQETG KPTLVIAHSM
GGLMVHGAVQ RNPKLFRSVV YVGSPSECLN ILGPIRFGDS VLLSDKILTF ETNFMMRSSF
IFLPLSGETF YNYKTKEKYK IDFFNPESWI EYNLNPLVSE KRKLEAEAKS KKLKDKDNSV
GRTLSMSSLG STKSPSPPSS VTSSSTFPSI NSISSKFSKM YRSSSLKKSK TSADSAASVP
ISSSSSSSTP PPPSSKGTTA SEPQPPAATT SVPGVDSTGN QSTPHPDHYS FTFAEAYRYL
SETLESTKKY ILSLEHDPKL AAEYPPMAIV YGNKIPSVRG SLVRSRQDIK DGNYYEFFYG
HGDGVIHQKW LMPEKKGFTF YDKHTGTGEI VGKFASDAAH VGLMTDFDTM GKALNAVFEA
EKCWEQKKLK QKRMMNQKLD
//
