ID G8BH75_CANPC Unreviewed; 513 AA.
AC G8BH75;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 28-JUN-2023, entry version 36.
DE RecName: Full=Enhancer of mRNA-decapping protein 3 {ECO:0000256|ARBA:ARBA00015797};
GN OrderedLocusNames=CPAR2_500250 {ECO:0000313|CGD:CAL0000156487,
GN ECO:0000313|EMBL:CCE43799.1};
OS Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia
OS parapsilosis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=578454 {ECO:0000313|EMBL:CCE43799.1, ECO:0000313|Proteomes:UP000005221};
RN [1] {ECO:0000313|Proteomes:UP000005221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 317 / ATCC MYA-4646 {ECO:0000313|Proteomes:UP000005221};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
RN [2] {ECO:0000313|Proteomes:UP000005221}
RP GENOME REANNOTATION.
RC STRAIN=CDC 317 / ATCC MYA-4646 {ECO:0000313|Proteomes:UP000005221};
RX PubMed=22192698; DOI=10.1186/1471-2164-12-628;
RA Guida A., Lindstaedt C., Maguire S.L., Ding C., Higgins D.G., Corton N.J.,
RA Berriman M., Butler G.;
RT "Using RNA-seq to determine the transcriptional landscape and the hypoxic
RT response of the pathogenic yeast Candida parapsilosis.";
RL BMC Genomics 12:628-628(2011).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, P-body
CC {ECO:0000256|ARBA:ARBA00004201}.
CC -!- SIMILARITY: Belongs to the EDC3 family.
CC {ECO:0000256|ARBA:ARBA00006610}.
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DR EMBL; HE605207; CCE43799.1; -; Genomic_DNA.
DR AlphaFoldDB; G8BH75; -.
DR STRING; 578454.G8BH75; -.
DR EnsemblFungi; CPAR2_500250-T; CPAR2_500250-T-p1; CPAR2_500250.
DR CGD; CAL0000156487; CPAR2_500250.
DR VEuPathDB; FungiDB:CPAR2_500250; -.
DR eggNOG; KOG2585; Eukaryota.
DR Proteomes; UP000005221; Chromosome 5.
DR GO; GO:0000932; C:P-body; IEA:UniProtKB-SubCell.
DR Gene3D; 3.40.50.10260; YjeF N-terminal domain; 1.
DR InterPro; IPR025762; DFDF.
DR InterPro; IPR019050; FDF_dom.
DR InterPro; IPR004443; YjeF_N_dom.
DR InterPro; IPR036652; YjeF_N_dom_sf.
DR PANTHER; PTHR13612:SF0; ENHANCER OF MRNA-DECAPPING PROTEIN 3; 1.
DR PANTHER; PTHR13612; UNCHARACTERIZED; 1.
DR Pfam; PF09532; FDF; 1.
DR Pfam; PF03853; YjeF_N; 1.
DR SMART; SM01199; FDF; 1.
DR SUPFAM; SSF64153; YjeF N-terminal domain-like; 1.
DR PROSITE; PS51512; DFDF; 1.
DR PROSITE; PS51385; YJEF_N; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000005221}.
FT DOMAIN 121..157
FT /note="DFDF"
FT /evidence="ECO:0000259|PROSITE:PS51512"
FT DOMAIN 252..488
FT /note="YjeF N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51385"
FT REGION 62..127
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 162..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 197..229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 71..88
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..127
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 513 AA; 57529 MW; 81E416960E3A09AA CRC64;
MTEFVQYEVV ITLKDNSTAR GTISYVDEKS ITLSNALTST DRKIQPSVEF LNTDIADLKV
SQLPPYRPKS NDQQKKSKKQ KNEDIVDDAI VYSSKPSRSN TPKPEKSKSK SKSRTESSDL
EPESIENVKN EEFDFEANLA MFDKKAVFED FKKNDHTSIS DRLVGHNKVE KPAKQKKQKY
DNDEMVLQDV ARDNWDQIGK SQENSRTNTP KSDGVKTQGR AQQNPTEARN RNFKLINSEN
ASPIQSASPV QLLEIERLSS DNFGVTPAMM AEICATNLSK LIIDRCLGGS VRLSNKKNHN
LPPLVLLLVG SGRCGSRAFA TGRHLSNHGV RVLAFVISSD ESDTELHHQW KIFESVGGKV
VTSSFDLLID IIRNQLNTPV ELIVDALQGY DDHLEDIFYE PQDKKTLTSL INWCNSSEQS
KVMSLDIPSG IDGGSGIPDD ELKVDCSWCI SMGLPLNGLL LAYKNNYLSD DDIVHYLIDV
GIPNKVFQTK QNLRKFDNFW YTAESSIKLD VEA
//
