ID G8BII7_CANPC Unreviewed; 665 AA.
AC G8BII7;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=ENTH domain-containing protein {ECO:0000259|PROSITE:PS50942};
GN OrderedLocusNames=CPAR2_402530 {ECO:0000313|CGD:CAL0000147037,
GN ECO:0000313|EMBL:CCE44452.1};
OS Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia
OS parapsilosis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=578454 {ECO:0000313|EMBL:CCE44452.1, ECO:0000313|Proteomes:UP000005221};
RN [1] {ECO:0000313|Proteomes:UP000005221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 317 / ATCC MYA-4646 {ECO:0000313|Proteomes:UP000005221};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
RN [2] {ECO:0000313|Proteomes:UP000005221}
RP GENOME REANNOTATION.
RC STRAIN=CDC 317 / ATCC MYA-4646 {ECO:0000313|Proteomes:UP000005221};
RX PubMed=22192698; DOI=10.1186/1471-2164-12-628;
RA Guida A., Lindstaedt C., Maguire S.L., Ding C., Higgins D.G., Corton N.J.,
RA Berriman M., Butler G.;
RT "Using RNA-seq to determine the transcriptional landscape and the hypoxic
RT response of the pathogenic yeast Candida parapsilosis.";
RL BMC Genomics 12:628-628(2011).
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DR EMBL; HE605208; CCE44452.1; -; Genomic_DNA.
DR AlphaFoldDB; G8BII7; -.
DR STRING; 578454.G8BII7; -.
DR EnsemblFungi; CPAR2_402530-T; CPAR2_402530-T-p1; CPAR2_402530.
DR CGD; CAL0000147037; CPAR2_402530.
DR VEuPathDB; FungiDB:CPAR2_402530; -.
DR eggNOG; KOG0251; Eukaryota.
DR Proteomes; UP000005221; Chromosome 4.
DR GO; GO:0030136; C:clathrin-coated vesicle; IEA:InterPro.
DR GO; GO:0005545; F:1-phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR GO; GO:0048268; P:clathrin coat assembly; IEA:InterPro.
DR GO; GO:0072583; P:clathrin-dependent endocytosis; IEA:InterPro.
DR CDD; cd16988; ANTH_N_YAP180; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 1.20.58.150; ANTH domain; 1.
DR InterPro; IPR011417; ANTH_dom.
DR InterPro; IPR014712; ANTH_dom_sf.
DR InterPro; IPR045192; AP180-like.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR PANTHER; PTHR22951; CLATHRIN ASSEMBLY PROTEIN; 1.
DR PANTHER; PTHR22951:SF89; PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN LAP; 1.
DR Pfam; PF07651; ANTH; 1.
DR SMART; SM00273; ENTH; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50942; ENTH; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000005221}.
FT DOMAIN 1..136
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT REGION 296..354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 485..665
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 394..473
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 315..354
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 485..656
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 665 AA; 76158 MW; 2B2C82A7FE5D8B5E CRC64;
MTTYEKIVKG ATKVKVAAPK PKYIEPILMA TSMDHSIISA DNFNTIMRTL QQRLRDSSWS
VVYKSLIVIH LMIREGDKDV ALRYLANQGH SMLNLSSSNI ASNNSGNYNA DVRLIMKYSK
YLHTRVKQFD ATGIDYVRDE RSNNSTTQEG GRLRSLSTEK GLLRETESVQ KQIDSLLKNS
FMENDINNDI VLTAFRLLVN DLLALFQELN EGVINILEHY FEMSKYDAER SLKVYKKFVD
QTKYVIDYLR VAKHLEYATK LHVPTIKHAP TALTSSLEEY LDDPNFEANR RQYLAEKGNK
QNADSPKKPI FGNRDETKTT PQQTQQQQQQ QQQQQKELSQ QQLPQQTLSN GGASGVDRHA
SLVVQQTYNP WNNIAIPVYA QAYTQQSQVD PYQLQQQQQQ EQAQQQQQAQ LQAQQQQQAQ
QLQAQQQQQA QLQIQQQQQA QLQAQQQQEQ AQQQAQQQQL QQQQQQLQQQ QQHTFGHQSR
LSLPPIIQGQ PYQSPMHTSY TGTGFGGYGS QTTLQPQLTN PMQQPLQPQS TNPFLQQQQQ
PQYTSTQFQQ QTPLPLQHQN TNPFLQKAQQ VQTAPAMQQH QQPQFTSQFT QPQMQLQSQS
SPGLQRSNTN PFARIVTGQQ NTQPQGGSFF GQQQPQQQQS IPPLQHQSTN PFARRTFDPN
VDSLI
//
