ID G8BJL4_CANPC Unreviewed; 604 AA.
AC G8BJL4;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Lysophospholipid acyltransferase {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=CPAR2_406330 {ECO:0000313|CGD:CAL0000156949,
GN ECO:0000313|EMBL:CCE44830.1};
OS Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia
OS parapsilosis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=578454 {ECO:0000313|EMBL:CCE44830.1, ECO:0000313|Proteomes:UP000005221};
RN [1] {ECO:0000313|Proteomes:UP000005221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 317 / ATCC MYA-4646 {ECO:0000313|Proteomes:UP000005221};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
RN [2] {ECO:0000313|Proteomes:UP000005221}
RP GENOME REANNOTATION.
RC STRAIN=CDC 317 / ATCC MYA-4646 {ECO:0000313|Proteomes:UP000005221};
RX PubMed=22192698; DOI=10.1186/1471-2164-12-628;
RA Guida A., Lindstaedt C., Maguire S.L., Ding C., Higgins D.G., Corton N.J.,
RA Berriman M., Butler G.;
RT "Using RNA-seq to determine the transcriptional landscape and the hypoxic
RT response of the pathogenic yeast Candida parapsilosis.";
RL BMC Genomics 12:628-628(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; HE605208; CCE44830.1; -; Genomic_DNA.
DR AlphaFoldDB; G8BJL4; -.
DR STRING; 578454.G8BJL4; -.
DR EnsemblFungi; CPAR2_406330-T; CPAR2_406330-T-p1; CPAR2_406330.
DR CGD; CAL0000156949; CPAR2_406330.
DR VEuPathDB; FungiDB:CPAR2_406330; -.
DR eggNOG; KOG2704; Eukaryota.
DR Proteomes; UP000005221; Chromosome 4.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR InterPro; IPR004299; MBOAT_fam.
DR PANTHER; PTHR13906:SF4; LYSOPHOSPHOLIPID ACYLTRANSFERASE 6; 1.
DR PANTHER; PTHR13906; PORCUPINE; 1.
DR Pfam; PF03062; MBOAT; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005221};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 70..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 123..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 419..442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 454..471
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 604 AA; 70657 MW; E481FD2A5CB28672 CRC64;
MVAFIQNWIN DLSDTVGLDP ASLKVLLCTL LSFPFGIIFK RIPDQQYFFK NIYNVLVSSF
YIFGICDLRW GLGTLVLSSL GSYFITRYLR TPKMPWINFL FLMIHMAYTH FHLQFFAEYD
PSVIDISGAQ MILVMKLSAF GWSVHDGKQP RDTLSDYNKS RAIYEHPNLL PFIGYAFFYA
SLLTGPAFDY MDYDHFIHST LFDDVPEDKR PGRKRKRRIP KSGRQALRKL LQGLFWAFLL
FEVPKLVSTE FVFSKQFVNE HGFVYRIFYM WLLGFLYRLK YYAIWLIAEG ACILCGIGYN
GYDPKTKEFR WDRVQNVDPI AFELGQNVHT CLEAWNQNTN KWLKHYIYLR VAKRGKKPGF
KSTVFTFATS AFWHGTRPGY YLTFVVGAFL QTVGKLFRRN IRPYCLESDG VTPKPTKRVY
DFVSWVCTQL AFGFVVQPFV ILDFKKSIIC WQTVYYWLLL VIAGSFFVYR GPFAKYFTVK
RSDSKTKAAA QQVKPQGFDS NLTKEENDLV MNVVENNLDK KDTMPTLGVP SFDDLQNLDK
DEFDEELHHL KDAWGSFKSR NFLAEDDFDG LKDAYTNFTQ EINEIFDRKK EEFSKQREKM
AKVD
//
