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Database: UniProt
Entry: G8BKM0_CANPC
LinkDB: G8BKM0_CANPC
Original site: G8BKM0_CANPC 
ID   G8BKM0_CANPC            Unreviewed;       234 AA.
AC   G8BKM0;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   05-JUN-2019, entry version 25.
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 9 {ECO:0000256|RuleBase:RU364145};
DE   AltName: Full=Mediator complex subunit 9 {ECO:0000256|RuleBase:RU364145};
GN   Name=MED9 {ECO:0000256|RuleBase:RU364145};
GN   OrderedLocusNames=CPAR2_702990 {ECO:0000313|CGD:CAL0000146843,
GN   ECO:0000313|EMBL:CCE45286.1};
OS   Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia
OS   parapsilosis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Debaryomycetaceae;
OC   Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=578454 {ECO:0000313|Proteomes:UP000005221};
RN   [1] {ECO:0000313|Proteomes:UP000005221}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 317 / ATCC MYA-4646 {ECO:0000313|Proteomes:UP000005221};
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L.,
RA   Agrafioti I., Arnaud M.B., Bates S., Brown A.J., Brunke S.,
RA   Costanzo M.C., Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L.,
RA   Hube B., Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R.,
RA   Neiman A.M., Nikolaou E., Quail M.A., Quinn J., Santos M.C.,
RA   Schmitzberger F.F., Sherlock G., Shah P., Silverstein K.A.,
RA   Skrzypek M.S., Soll D., Staggs R., Stansfield I., Stumpf M.P.,
RA   Sudbery P.E., Srikantha T., Zeng Q., Berman J., Berriman M.,
RA   Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
RN   [2] {ECO:0000313|Proteomes:UP000005221}
RP   GENOME REANNOTATION.
RC   STRAIN=CDC 317 / ATCC MYA-4646 {ECO:0000313|Proteomes:UP000005221};
RX   PubMed=22192698; DOI=10.1186/1471-2164-12-628;
RA   Guida A., Lindstaedt C., Maguire S.L., Ding C., Higgins D.G.,
RA   Corton N.J., Berriman M., Butler G.;
RT   "Using RNA-seq to determine the transcriptional landscape and the
RT   hypoxic response of the pathogenic yeast Candida parapsilosis.";
RL   BMC Genomics 12:628-628(2011).
CC   -!- FUNCTION: Component of the Mediator complex, a coactivator
CC       involved in the regulated transcription of nearly all RNA
CC       polymerase II-dependent genes. Mediator functions as a bridge to
CC       convey information from gene-specific regulatory proteins to the
CC       basal RNA polymerase II transcription machinery. Mediator is
CC       recruited to promoters by direct interactions with regulatory
CC       proteins and serves as a scaffold for the assembly of a functional
CC       preinitiation complex with RNA polymerase II and the general
CC       transcription factors. {ECO:0000256|RuleBase:RU364145}.
CC   -!- SUBUNIT: Component of the Mediator complex.
CC       {ECO:0000256|RuleBase:RU364145}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU364145}.
CC   -!- SIMILARITY: Belongs to the Mediator complex subunit 9 family.
CC       {ECO:0000256|RuleBase:RU364145}.
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DR   EMBL; HE605209; CCE45286.1; -; Genomic_DNA.
DR   STRING; 5480.G8BKM0; -.
DR   EnsemblFungi; CCE45286; CCE45286; CPAR2_702990.
DR   CGD; CAL0000146843; CPAR2_702990.
DR   Proteomes; UP000005221; Chromosome 7.
DR   GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR   GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   InterPro; IPR011425; Med9.
DR   Pfam; PF07544; Med9; 1.
PE   3: Inferred from homology;
KW   Activator {ECO:0000256|RuleBase:RU364145};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005221};
KW   Nucleus {ECO:0000256|RuleBase:RU364145};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005221};
KW   Transcription {ECO:0000256|RuleBase:RU364145};
KW   Transcription regulation {ECO:0000256|RuleBase:RU364145}.
FT   REGION        1     91       Disordered. {ECO:0000256|MobiDB-lite:
FT                                G8BKM0}.
FT   COILED      208    228       {ECO:0000256|SAM:Coils}.
FT   COMPBIAS     17     50       Polar. {ECO:0000256|MobiDB-lite:G8BKM0}.
FT   COMPBIAS     52     75       Polyampholyte. {ECO:0000256|MobiDB-lite:
FT                                G8BKM0}.
SQ   SEQUENCE   234 AA;  25887 MW;  50AE60DEEB901BE8 CRC64;
     MDTPIGLDGT IGSDFSLDNH DDLTQFSQLE SLGDSEQGST TVQLPDPASS SVPSEDKEEE
     PASNQVKKEE GQTNDLGHQE QSGGYSKPES PHTELLEKMD IDMPDASQSA TELEPPFKAA
     PEAATNDVAI ASTATNTDNQ DDPLAKIKQI QLLPELYNIL FDFTNGKIHP RDFDKHIGNL
     RSKLDNLKSY ISEIDGIDVT PEIMMNEINR LKENNVKKQT LLNSFRNKIK NDFV
//
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