ID   G8BMP6_TETPH            Unreviewed;       383 AA.
AC   G8BMP6;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   RecName: Full=Inositol polyphosphate-related phosphatase domain-containing protein {ECO:0000259|SMART:SM00128};
GN   Name=TPHA0A00890 {ECO:0000313|EMBL:CCE61174.1};
GN   OrderedLocusNames=TPHA_0A00890 {ECO:0000313|EMBL:CCE61174.1};
OS   Tetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL
OS   Y-8282 / UCD 70-5) (Yeast) (Fabospora phaffii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Tetrapisispora.
OX   NCBI_TaxID=1071381 {ECO:0000313|EMBL:CCE61174.1, ECO:0000313|Proteomes:UP000005666};
RN   [1] {ECO:0000313|EMBL:CCE61174.1, ECO:0000313|Proteomes:UP000005666}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5
RC   {ECO:0000313|Proteomes:UP000005666};
RX   PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA   Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA   Wolfe K.H.;
RT   "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT   accidents.";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
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DR   EMBL; HE612856; CCE61174.1; -; Genomic_DNA.
DR   RefSeq; XP_003683608.1; XM_003683560.1.
DR   AlphaFoldDB; G8BMP6; -.
DR   STRING; 1071381.G8BMP6; -.
DR   GeneID; 11532754; -.
DR   KEGG; tpf:TPHA_0A00890; -.
DR   eggNOG; KOG0565; Eukaryota.
DR   HOGENOM; CLU_025224_2_0_1; -.
DR   OMA; FNCARNP; -.
DR   OrthoDB; 1329119at2759; -.
DR   Proteomes; UP000005666; Chromosome 1.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:UniProt.
DR   GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:InterPro.
DR   Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR   InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR   InterPro; IPR046985; IP5.
DR   InterPro; IPR000300; IPPc.
DR   PANTHER; PTHR11200; INOSITOL 5-PHOSPHATASE; 1.
DR   PANTHER; PTHR11200:SF281; PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 5-PHOSPHATASE INP54; 1.
DR   SMART; SM00128; IPPc; 1.
DR   SUPFAM; SSF56219; DNase I-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005666};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        365..382
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          2..325
FT                   /note="Inositol polyphosphate-related phosphatase"
FT                   /evidence="ECO:0000259|SMART:SM00128"
SQ   SEQUENCE   383 AA;  43063 MW;  8B55B7B732EC4EC2 CRC64;
     MNDWKISVTT FNCGKKYPVD NSTWSAKIIK ECLAGLSDAQ DIYVFGFQEF VPLWEGSFHD
     TVSSYLDEVA STTIDILSKQ FNGKTFKSIG SHSLGAIALL VIASNTVIKK SSILSVECSR
     GLLGSNLKGG IAISVDLANR KENHGNNKET FTFINTHLAA NEGMQNASTR IDDINCILNT
     CDRELRMTNF KNGHLFVLGD MNFRLTNINK DASQLDFTDA VVIQELLKNN DELNLFKLIS
     GFIFSGFIEP TITFAPTYKY KIDCPDEYNY KRTPSWCDRI LFKEYGNADK VKIINYNSIA
     RADCLQFTDH QPVTLSLSIP TTAECTQLTL PDFIQPEEYY KVVGSILNTS VGYSGWLLSF
     KYSKLIAIVL LVIWTVWILN AWK
//