ID G8BP71_TETPH Unreviewed; 316 AA.
AC G8BP71;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Translation initiation factor eIF2B subunit alpha {ECO:0000256|ARBA:ARBA00044208};
DE AltName: Full=eIF2B GDP-GTP exchange factor subunit alpha {ECO:0000256|ARBA:ARBA00044236};
GN Name=TPHA0B01290 {ECO:0000313|EMBL:CCE61802.1};
GN OrderedLocusNames=TPHA_0B01290 {ECO:0000313|EMBL:CCE61802.1};
OS Tetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL
OS Y-8282 / UCD 70-5) (Yeast) (Fabospora phaffii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Tetrapisispora.
OX NCBI_TaxID=1071381 {ECO:0000313|EMBL:CCE61802.1, ECO:0000313|Proteomes:UP000005666};
RN [1] {ECO:0000313|EMBL:CCE61802.1, ECO:0000313|Proteomes:UP000005666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5
RC {ECO:0000313|Proteomes:UP000005666};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}.
CC -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits family.
CC {ECO:0000256|ARBA:ARBA00007251, ECO:0000256|RuleBase:RU003814}.
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DR EMBL; HE612857; CCE61802.1; -; Genomic_DNA.
DR RefSeq; XP_003684236.1; XM_003684188.1.
DR AlphaFoldDB; G8BP71; -.
DR STRING; 1071381.G8BP71; -.
DR GeneID; 11535099; -.
DR KEGG; tpf:TPHA_0B01290; -.
DR eggNOG; KOG1466; Eukaryota.
DR HOGENOM; CLU_016218_0_2_1; -.
DR OMA; GDWESCK; -.
DR OrthoDB; 51607at2759; -.
DR Proteomes; UP000005666; Chromosome 2.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR Gene3D; 1.20.120.1070; Translation initiation factor eIF-2B, N-terminal domain; 1.
DR InterPro; IPR042528; elF-2B_alpha_N.
DR InterPro; IPR000649; IF-2B-related.
DR InterPro; IPR042529; IF_2B-like_C.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR PANTHER; PTHR45860; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA; 1.
DR PANTHER; PTHR45860:SF1; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA; 1.
DR Pfam; PF01008; IF-2B; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000005666}.
SQ SEQUENCE 316 AA; 35059 MW; B4BA841145D35D11 CRC64;
MSEFNITETY LGFLEEDTEV TMPIAAIEAL VTLLTVKNPE TAAEMINSIK SATEELINSI
PNSMSLRAGC DVFMRFVLKN TQLYGDWESC KRHLIENGQL FVSRSKQSRD KIAKIGKDFI
TDDDTILLHG HSRAVFSLLS HAAENFIRFR CVITESRPSD QGIRCYNALK AKGIPVTMIV
DSAVGSIIHR IDKVFVGAEG VTESGGIVNI IGTYSIGVLA KIARKPFFVV SESHKFVRMF
PLSPDDLPLV GDSLNFNRSD NAIAANTDKL EDNDFDITQG RKTDYTSQDY ITALITDLGV
LTPSAVSEEL IKMWYD
//
