ID G8BUN5_TETPH Unreviewed; 388 AA.
AC G8BUN5;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Aromatic amino acid beta-eliminating lyase/threonine aldolase domain-containing protein {ECO:0000259|Pfam:PF01212};
GN Name=TPHA0F03410 {ECO:0000313|EMBL:CCE63821.1};
GN OrderedLocusNames=TPHA_0F03410 {ECO:0000313|EMBL:CCE63821.1};
OS Tetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL
OS Y-8282 / UCD 70-5) (Yeast) (Fabospora phaffii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Tetrapisispora.
OX NCBI_TaxID=1071381 {ECO:0000313|EMBL:CCE63821.1, ECO:0000313|Proteomes:UP000005666};
RN [1] {ECO:0000313|EMBL:CCE63821.1, ECO:0000313|Proteomes:UP000005666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5
RC {ECO:0000313|Proteomes:UP000005666};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the threonine aldolase family.
CC {ECO:0000256|ARBA:ARBA00006966}.
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DR EMBL; HE612861; CCE63821.1; -; Genomic_DNA.
DR RefSeq; XP_003686255.1; XM_003686207.1.
DR AlphaFoldDB; G8BUN5; -.
DR STRING; 1071381.G8BUN5; -.
DR GeneID; 11535446; -.
DR KEGG; tpf:TPHA_0F03410; -.
DR eggNOG; KOG1368; Eukaryota.
DR HOGENOM; CLU_029381_1_0_1; -.
DR OMA; LVRIKAW; -.
DR OrthoDB; 178754at2759; -.
DR Proteomes; UP000005666; Chromosome 6.
DR GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR CDD; cd06502; TA_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR InterPro; IPR023603; Low_specificity_L-TA-like.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR NCBIfam; NF041359; GntG_guanitoxin; 1.
DR PANTHER; PTHR48097:SF9; L-THREONINE ALDOLASE; 1.
DR PANTHER; PTHR48097; L-THREONINE ALDOLASE-RELATED; 1.
DR Pfam; PF01212; Beta_elim_lyase; 1.
DR PIRSF; PIRSF017617; Thr_aldolase; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005666}.
FT DOMAIN 16..302
FT /note="Aromatic amino acid beta-eliminating lyase/threonine
FT aldolase"
FT /evidence="ECO:0000259|Pfam:PF01212"
FT MOD_RES 213
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR017617-1"
SQ SEQUENCE 388 AA; 43020 MW; 4CE281B065EED364 CRC64;
MSEFELPPNY VSASNDFRSD TFTTPTSEMI QVALSATKGD AVYGEDTDTV LLEKTIAKTF
GYDAGLFCVS GTLSNQIALR THLTQPPYSI LCDYRAHVYT HEAAGLAILS QSMVVPVIPS
NGNYLTLEDI QSHYIPDDGD IHGAPTRVIS LENTLHGILY PLEELFRIRT WCKANNLLLH
CDGARIFNAC AESGVPSKQF AEIFDSISVC LSKSVGAPIG SVLVGDVKFI KKANHFRKQQ
GGGIRQSGMI SRMALYCVDG DWKEKIRYSH SLAHNLAAFC KQEGIPLESP ADTNFVFIDL
QKAKMDPDVL VKKGLKYGVK LMGGRVSFHY QISNESLEKV KLAVKESFEY AKTHPYSQNG
PTQIYRSEST EKMDVDGNAI RDIKTYKY
//
