ID G8BUW4_TETPH Unreviewed; 378 AA.
AC G8BUW4;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Methionyl-tRNA formyltransferase, mitochondrial {ECO:0000256|ARBA:ARBA00014185};
DE EC=2.1.2.9 {ECO:0000256|ARBA:ARBA00012261};
GN Name=TPHA0F00590 {ECO:0000313|EMBL:CCE63546.1};
GN OrderedLocusNames=TPHA_0F00590 {ECO:0000313|EMBL:CCE63546.1};
OS Tetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL
OS Y-8282 / UCD 70-5) (Yeast) (Fabospora phaffii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Tetrapisispora.
OX NCBI_TaxID=1071381 {ECO:0000313|EMBL:CCE63546.1, ECO:0000313|Proteomes:UP000005666};
RN [1] {ECO:0000313|EMBL:CCE63546.1, ECO:0000313|Proteomes:UP000005666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5
RC {ECO:0000313|Proteomes:UP000005666};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
CC -!- SIMILARITY: Belongs to the Fmt family. {ECO:0000256|ARBA:ARBA00010699}.
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DR EMBL; HE612861; CCE63546.1; -; Genomic_DNA.
DR RefSeq; XP_003685980.1; XM_003685932.1.
DR AlphaFoldDB; G8BUW4; -.
DR STRING; 1071381.G8BUW4; -.
DR GeneID; 11535608; -.
DR KEGG; tpf:TPHA_0F00590; -.
DR eggNOG; KOG3082; Eukaryota.
DR HOGENOM; CLU_033347_0_1_1; -.
DR OMA; MWIIPGP; -.
DR OrthoDB; 179280at2759; -.
DR Proteomes; UP000005666; Chromosome 6.
DR GO; GO:0004479; F:methionyl-tRNA formyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd08646; FMT_core_Met-tRNA-FMT_N; 1.
DR Gene3D; 3.40.50.12230; -; 1.
DR InterPro; IPR005794; Fmt.
DR InterPro; IPR005793; Formyl_trans_C.
DR InterPro; IPR002376; Formyl_transf_N.
DR InterPro; IPR036477; Formyl_transf_N_sf.
DR InterPro; IPR041711; Met-tRNA-FMT_N.
DR NCBIfam; TIGR00460; fmt; 1.
DR PANTHER; PTHR11138; METHIONYL-TRNA FORMYLTRANSFERASE; 1.
DR PANTHER; PTHR11138:SF5; METHIONYL-TRNA FORMYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF02911; Formyl_trans_C; 1.
DR Pfam; PF00551; Formyl_trans_N; 1.
DR SUPFAM; SSF53328; Formyltransferase; 1.
PE 3: Inferred from homology;
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000005666};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 32..187
FT /note="Formyl transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00551"
FT DOMAIN 255..363
FT /note="Formyl transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02911"
SQ SEQUENCE 378 AA; 42639 MW; EF8524FC8604524D CRC64;
MFAQLTAWKV KRLVFKRCQH GIGSHSLSSL DVLFFGSDEF SIHALDSLRS LQNNYPPLVK
DIQVVTRKPK WCGRYKSVLK HTPIVEHCKT IGLREPLLCD SKQDMLDIGD VHNYDMVVAV
SFGKLIPSKL LSKAKYSLNI HPSLLPRYKG ASPIQYALLN RDTETGVTIQ TLHPNKFDHG
RIIAQTRPLS TSDLLAKGVV SEFPEKTPIY TAILMDQLGL VGGELLKKVI SEQLYTDQNK
SIESGQVFEA SYASRITSAM KQISWNTDEA IDLVVRLNTL GPLFAPIKVL MRKNGNVNKR
IIFHDFTVCS NYQEKLGSPG QFCYDDKSMT VVVCCANNSY IQVKSLQFEG FTVETASEFV
RRFRKRCGNK TESTFEFV
//
