ID G8BXM5_TETPH Unreviewed; 954 AA.
AC G8BXM5;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=DNA mismatch repair proteins mutS family domain-containing protein {ECO:0000259|PROSITE:PS00486};
GN Name=TPHA0I01470 {ECO:0000313|EMBL:CCE64653.1};
GN OrderedLocusNames=TPHA_0I01470 {ECO:0000313|EMBL:CCE64653.1};
OS Tetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL
OS Y-8282 / UCD 70-5) (Yeast) (Fabospora phaffii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Tetrapisispora.
OX NCBI_TaxID=1071381 {ECO:0000313|EMBL:CCE64653.1, ECO:0000313|Proteomes:UP000005666};
RN [1] {ECO:0000313|EMBL:CCE64653.1, ECO:0000313|Proteomes:UP000005666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5
RC {ECO:0000313|Proteomes:UP000005666};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271}.
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DR EMBL; HE612864; CCE64653.1; -; Genomic_DNA.
DR RefSeq; XP_003687087.1; XM_003687039.1.
DR AlphaFoldDB; G8BXM5; -.
DR STRING; 1071381.G8BXM5; -.
DR GeneID; 11534512; -.
DR KEGG; tpf:TPHA_0I01470; -.
DR eggNOG; ENOG502QUUG; Eukaryota.
DR HOGENOM; CLU_002472_4_0_1; -.
DR OMA; KSYGIFC; -.
DR OrthoDB; 168255at2759; -.
DR Proteomes; UP000005666; Chromosome 9.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361:SF34; DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000005666}.
FT DOMAIN 840..856
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT COILED 565..592
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 954 AA; 108511 MW; 07C48D76CD7FD9AE CRC64;
MYRCITARLC PYRSIIHYRN FAKVNTKPSV SKIKIQTTSP KLNAQNKLDS YINTTNTLPD
LNKDIATATP DVDEKLSDIP PSLKYVRELI DHHKGSVVLT QMGSFYELYF EQAEKYAPEL
NIQLTSKQFS HGKVPFAGFP VGQLSRHLKV LVNDHEYSVA IAQQFKKDGV ADNEVSKFYR
RVTRIVTPGT FIDEAFENFE ENNYLLSINF PENCFNKLAD SDSKLGLSWC DVSTGEIFVQ
QVRLKDAVSA ITRIQPKEIL LEESIADFTI ESGSWYPEFV ELKKYFLKYH KLPAAHITLD
SLYSLFANGT EESTSRLFKI QFQTFTQKEL AALRDLLIYI KEHLPDFRMN LQFPQKQSVT
SIMQIDSRTS SALELHATVR DRSKKGSLLS CIRRTVTSPG TRLLSQWLSG PSLDLAEINS
RQDIVAFFLE DLDSTKDMIS NLKTVSDLTR IIQRFSFNQG DASELLQLVE SLKTAKAVKK
NIETINSELE DNKLPDELYN RLISDLEFDG SLISEVESCI NEVALRKINS ATSEGIEKDE
SMNSSGIHDT NNEIWIIDPN YNNSLKKYHE EYQNCKREKE KLQEIYNNKL VNDIGCRRVA
MKQKPNGDYT LHIHASTNNM KKVLDFINTK ELINGHPLVI TQKSVQTCWV SHKSWNDLAH
LSELAKFRIK QEEDFILNNL KTKFVNKSES IRLITHKLAY IDVLSSFAIL ATDNRLKRPK
LNNTTSFNIK GGRHLMVEEG LKISSLSTFV KNDCKLAKGD LWVITGPNMG GKSTFLRQNA
TIIILAQIGS YCPCDKATIG LVDKIFSRVG SADDLYNEMS TFMVEMIETS YILHGATNRS
LAILDEIGRG TSSKEGTSIA FATLKYLIEK NSCRTLFATH FGSELKEIID KNYYDSLKNN
LKFYETSVVE ISEDNYYYDH KLKEGVCTKS DAIKVAKRAG FPETALNDAK RFLN
//
