ID G8BYW3_TETPH Unreviewed; 211 AA.
AC G8BYW3;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit KXD1 {ECO:0000256|ARBA:ARBA00016207};
DE AltName: Full=KxDL homolog {ECO:0000256|ARBA:ARBA00029808};
GN Name=TPHA0J02350 {ECO:0000313|EMBL:CCE65055.1};
GN OrderedLocusNames=TPHA_0J02350 {ECO:0000313|EMBL:CCE65055.1};
OS Tetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL
OS Y-8282 / UCD 70-5) (Yeast) (Fabospora phaffii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Tetrapisispora.
OX NCBI_TaxID=1071381 {ECO:0000313|EMBL:CCE65055.1, ECO:0000313|Proteomes:UP000005666};
RN [1] {ECO:0000313|EMBL:CCE65055.1, ECO:0000313|Proteomes:UP000005666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5
RC {ECO:0000313|Proteomes:UP000005666};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
CC -!- FUNCTION: Component of the biogenesis of lysosome-related organelles
CC complex-1 (BLOC-1) involved in endosomal cargo sorting.
CC {ECO:0000256|ARBA:ARBA00002069}.
CC -!- SUBCELLULAR LOCATION: Endosome {ECO:0000256|ARBA:ARBA00004177}.
CC -!- SIMILARITY: Belongs to the KXD1 family.
CC {ECO:0000256|ARBA:ARBA00005913}.
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DR EMBL; HE612865; CCE65055.1; -; Genomic_DNA.
DR RefSeq; XP_003687489.1; XM_003687441.1.
DR AlphaFoldDB; G8BYW3; -.
DR STRING; 1071381.G8BYW3; -.
DR GeneID; 11533185; -.
DR KEGG; tpf:TPHA_0J02350; -.
DR eggNOG; ENOG502S1H5; Eukaryota.
DR HOGENOM; CLU_099155_0_0_1; -.
DR OMA; TPMFDTS; -.
DR OrthoDB; 2030018at2759; -.
DR Proteomes; UP000005666; Chromosome 10.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-SubCell.
DR InterPro; IPR019371; KxDL_dom.
DR PANTHER; PTHR37787; BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT KXD1; 1.
DR PANTHER; PTHR37787:SF1; BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT KXD1; 1.
DR Pfam; PF10241; KxDL; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005666}.
FT DOMAIN 114..198
FT /note="KxDL"
FT /evidence="ECO:0000259|Pfam:PF10241"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 40..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..61
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 211 AA; 22630 MW; 9DDB927C56A17A7F CRC64;
MSSNGSIVSG NSGHVEGSVA SPSINSMSYA IPVSDDIIAN LSEESTSEDV SDASEGSGGK
NGDNSESERD DLLNDETLDK IINNSNINVF ESSDAVSTSE PLLMDVSKCI FGLLKQSLDA
ADFSESLSLQ TKTSATVNAK TLELKQLVDS ASQTLIRLKQ RFETGKETAK RIQRNLNSAR
SSIDILNGRL RTDHPIEFSQ SRDKAMNGHN A
//
