ID G8F4K9_MACFA Unreviewed; 411 AA.
AC G8F4K9;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Sushi domain-containing protein {ECO:0000259|PROSITE:PS50923};
DE Flags: Fragment;
GN ORFNames=EGM_20464 {ECO:0000313|EMBL:EHH62223.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Proteomes:UP000009130};
RN [1] {ECO:0000313|EMBL:EHH62223.1, ECO:0000313|Proteomes:UP000009130}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CE-4 {ECO:0000313|EMBL:EHH62223.1,
RC ECO:0000313|Proteomes:UP000009130};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
CC -!- SIMILARITY: Belongs to the receptors of complement activation (RCA)
CC family. {ECO:0000256|ARBA:ARBA00010908}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR EMBL; JH330887; EHH62223.1; -; Genomic_DNA.
DR AlphaFoldDB; G8F4K9; -.
DR eggNOG; ENOG502SKPE; Eukaryota.
DR Proteomes; UP000009130; Unassembled WGS sequence.
DR CDD; cd00033; CCP; 4.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 4.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR19325; COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR19325:SF317; COMPLEMENT DECAY-ACCELERATING FACTOR; 1.
DR Pfam; PF00084; Sushi; 4.
DR SMART; SM00032; CCP; 4.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 4.
DR PROSITE; PS50923; SUSHI; 4.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Sushi {ECO:0000256|ARBA:ARBA00022659, ECO:0000256|PROSITE-
KW ProRule:PRU00302}.
FT DOMAIN 1..63
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 64..127
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 128..189
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 190..252
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT REGION 270..323
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 270..305
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EHH62223.1"
FT NON_TER 411
FT /evidence="ECO:0000313|EMBL:EHH62223.1"
SQ SEQUENCE 411 AA; 45771 MW; 08D381852D64D6A5 CRC64;
ADCGPPPAVP NAQPALKGLT SFPENTVITY RCDENFMKIP GKQDSVMCLP DSQWSDIEEF
CNRSCGAPTR LKFASLKQLY IPQSYFPVGT VVEYECRPGY RRDPSLLAKL TCLQNLKWST
AAEFCKKKSC PNPGEIPNGQ IDTSNGILFG AAISFSCNTG YKLFGPTSSL CLVSGSGVQW
SDTLPECREI YCPAPPQIDN GIIQGEREHY GYRQSITYLC NRGFTMIGEH SIYCTVNDDE
GEWSGPPPAC RANSLVSKAP PTVQKPTTVN VRTTEVSPTS QKTTTPNAQD HITATRSTPA
SRTTKHFHKT TPDKGSGTSS GQLTLFRGSH PVTQAGMRWC IHSSLQSRTP GLKRSFHFSL
PSSWYYRCVP RHMAKFFKFI FCRDRISLCC PGWFRTPGRK RFFRPPKTLR L
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