ID   G8JM05_ERECY            Unreviewed;       364 AA.
AC   G8JM05;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   RecName: Full=L-serine ammonia-lyase {ECO:0000256|ARBA:ARBA00012093};
DE            EC=4.3.1.17 {ECO:0000256|ARBA:ARBA00012093};
GN   OrderedLocusNames=Ecym_1006 {ECO:0000313|EMBL:AET37265.1};
OS   Eremothecium cymbalariae (strain CBS 270.75 / DBVPG 7215 / KCTC 17166 /
OS   NRRL Y-17582) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=931890 {ECO:0000313|EMBL:AET37265.1, ECO:0000313|Proteomes:UP000006790};
RN   [1] {ECO:0000313|Proteomes:UP000006790}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 270.75 / DBVPG 7215 / KCTC 17166 / NRRL Y-17582
RC   {ECO:0000313|Proteomes:UP000006790};
RX   DOI=10.1534/g3.111.000745;
RA   Leh Louis V., Despons L., Friedrich A., Martin T., Durrens P.,
RA   Casaregola S., Neuveglise C., Fairhead C., Marck C., Cruz J.A.,
RA   Straub M.L., Kugler V., Sacerdot C., Uzunov Z., Thierry A., Weiss S.,
RA   Bleykasten C., De Montigny J., Jacques N., Jung P., Lemaire M., Mallet S.,
RA   Morel G., Richard G.F., Sarkar A., Savel G., Schacherer J., Seret M.L.,
RA   Talla E., Samson G., Jubin C., Poulain J., Vacherie B., Barbe V.,
RA   Pelletier E., Sherman D.J., Westhof E., Weissenbach J., Baret P.V.,
RA   Wincker P., Gaillardin C., Dujon B., Souciet J.L.;
RT   "Pichia sorbitophila, an interspecies yeast hybrid reveals early steps of
RT   genome resolution following polyploidization.";
RL   G3 (Bethesda) 2:299-311(2012).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
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DR   EMBL; CP002497; AET37265.1; -; Genomic_DNA.
DR   RefSeq; XP_003644082.1; XM_003644034.1.
DR   AlphaFoldDB; G8JM05; -.
DR   STRING; 931890.G8JM05; -.
DR   GeneID; 11470371; -.
DR   KEGG; erc:Ecym_1006; -.
DR   eggNOG; KOG1250; Eukaryota.
DR   HOGENOM; CLU_021152_3_1_1; -.
DR   InParanoid; G8JM05; -.
DR   OMA; AEQGCEH; -.
DR   OrthoDB; 8406at2759; -.
DR   Proteomes; UP000006790; Chromosome 1.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   CDD; cd06448; L-Ser-dehyd; 1.
DR   Gene3D; 3.40.50.1100; -; 2.
DR   InterPro; IPR000634; Ser/Thr_deHydtase_PyrdxlP-BS.
DR   InterPro; IPR001926; TrpB-like_PALP.
DR   InterPro; IPR036052; TrpB-like_PALP_sf.
DR   PANTHER; PTHR48078:SF2; CATABOLIC L-SERINE_THREONINE DEHYDRATASE; 1.
DR   PANTHER; PTHR48078; THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED; 1.
DR   Pfam; PF00291; PALP; 1.
DR   SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
DR   PROSITE; PS00165; DEHYDRATASE_SER_THR; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000006790}.
FT   DOMAIN          5..325
FT                   /note="Tryptophan synthase beta chain-like PALP"
FT                   /evidence="ECO:0000259|Pfam:PF00291"
SQ   SEQUENCE   364 AA;  39732 MW;  FAFCA8F146C29107 CRC64;
     MSSLYVKTPL LRRAFGKPNI QISKVPQFLV KYEFFQPSGS FKSRGIGNLI YNKVSEIRRD
     PAKQPHVFSS SGGNAGLAAA TASQRMGIPC TVVVPTSTRQ RIIEKIMATG ATIICRGDYF
     AEADSYLKDL MQEAANKNTR DKKNVPIYVH PFNHPLIWHG HSYIVEEILE SLRNENIPYS
     RVKGIVCSVG GGGLYNGIIE GLERHSLANT IPIIGVETEG CEVLHKSLIA GKLITFKKAL
     SVATSLSVPT ITKETLRYAQ KYKTKSLVLG EGEVLDTCLR FTDESNIVTE PACGATLHLG
     YHPAILHKEL GPLSSEDIVI LIACGGSATT LADLRELKLK YNPVTLDDSP VEIPGLITEQ
     VLTA
//