ID G8JNL2_ERECY Unreviewed; 321 AA.
AC G8JNL2;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=rRNA methyltransferase 2, mitochondrial {ECO:0000256|ARBA:ARBA00041184};
GN OrderedLocusNames=Ecym_2178 {ECO:0000313|EMBL:AET37928.1};
OS Eremothecium cymbalariae (strain CBS 270.75 / DBVPG 7215 / KCTC 17166 /
OS NRRL Y-17582) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=931890 {ECO:0000313|EMBL:AET37928.1, ECO:0000313|Proteomes:UP000006790};
RN [1] {ECO:0000313|Proteomes:UP000006790}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 270.75 / DBVPG 7215 / KCTC 17166 / NRRL Y-17582
RC {ECO:0000313|Proteomes:UP000006790};
RX DOI=10.1534/g3.111.000745;
RA Leh Louis V., Despons L., Friedrich A., Martin T., Durrens P.,
RA Casaregola S., Neuveglise C., Fairhead C., Marck C., Cruz J.A.,
RA Straub M.L., Kugler V., Sacerdot C., Uzunov Z., Thierry A., Weiss S.,
RA Bleykasten C., De Montigny J., Jacques N., Jung P., Lemaire M., Mallet S.,
RA Morel G., Richard G.F., Sarkar A., Savel G., Schacherer J., Seret M.L.,
RA Talla E., Samson G., Jubin C., Poulain J., Vacherie B., Barbe V.,
RA Pelletier E., Sherman D.J., Westhof E., Weissenbach J., Baret P.V.,
RA Wincker P., Gaillardin C., Dujon B., Souciet J.L.;
RT "Pichia sorbitophila, an interspecies yeast hybrid reveals early steps of
RT genome resolution following polyploidization.";
RL G3 (Bethesda) 2:299-311(2012).
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. RNA methyltransferase RlmE family.
CC {ECO:0000256|ARBA:ARBA00009258}.
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DR EMBL; CP002498; AET37928.1; -; Genomic_DNA.
DR RefSeq; XP_003644745.1; XM_003644697.1.
DR AlphaFoldDB; G8JNL2; -.
DR STRING; 931890.G8JNL2; -.
DR GeneID; 11473025; -.
DR KEGG; erc:Ecym_2178; -.
DR eggNOG; KOG4589; Eukaryota.
DR HOGENOM; CLU_009422_2_0_1; -.
DR InParanoid; G8JNL2; -.
DR OMA; HRQTDHL; -.
DR OrthoDB; 2785996at2759; -.
DR Proteomes; UP000006790; Chromosome 2.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProt.
DR GO; GO:0001510; P:RNA methylation; IEA:InterPro.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR HAMAP; MF_01547; RNA_methyltr_E; 1.
DR InterPro; IPR002877; RNA_MeTrfase_FtsJ_dom.
DR InterPro; IPR015507; rRNA-MeTfrase_E.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR10920; RIBOSOMAL RNA METHYLTRANSFERASE; 1.
DR PANTHER; PTHR10920:SF18; RRNA METHYLTRANSFERASE 2, MITOCHONDRIAL; 1.
DR Pfam; PF01728; FtsJ; 1.
DR PIRSF; PIRSF005461; 23S_rRNA_mtase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000006790};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PIRSR:PIRSR005461-1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 60..305
FT /note="Ribosomal RNA methyltransferase FtsJ"
FT /evidence="ECO:0000259|Pfam:PF01728"
FT ACT_SITE 263
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005461-1"
SQ SEQUENCE 321 AA; 37325 MW; E9E097F3EA6B1A7C CRC64;
MEWIGRVGCV ELVPMLSRVF RKRWVVGVDV GRRFNSSSNR WVNRQQNDFY TKEAKVQNLR
SRAAFKLIEL DDKFHIFKKN CSQRVLDLGF APGAWSQVAY DRTLPNGKVL GVDILPCRPP
KGVSSLQANI LSRKTHELIR LYFSQSFKFN RHDNLDKNYG YFQHMLEEEL SRSKNSYEYK
DTALESESPT VAEYPLDVII SDMYEPWPQT TGYWNNFTNV AYYRMANTTG LVIKDHYMSM
DLCDAALLCA IGLLRPGGSF ICKLYTGKED ILLENRMKQV FKKVRRSKPK ASHKDSKELY
FVGLDKRENV DRFEVFTSPS E
//
