ID   G8JP86_ERECY            Unreviewed;       440 AA.
AC   G8JP86;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   RecName: Full=Ribosome biogenesis protein NOP53 {ECO:0000256|ARBA:ARBA00018339, ECO:0000256|PIRNR:PIRNR017302};
GN   OrderedLocusNames=Ecym_2412 {ECO:0000313|EMBL:AET38144.1};
OS   Eremothecium cymbalariae (strain CBS 270.75 / DBVPG 7215 / KCTC 17166 /
OS   NRRL Y-17582) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=931890 {ECO:0000313|EMBL:AET38144.1, ECO:0000313|Proteomes:UP000006790};
RN   [1] {ECO:0000313|Proteomes:UP000006790}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 270.75 / DBVPG 7215 / KCTC 17166 / NRRL Y-17582
RC   {ECO:0000313|Proteomes:UP000006790};
RX   DOI=10.1534/g3.111.000745;
RA   Leh Louis V., Despons L., Friedrich A., Martin T., Durrens P.,
RA   Casaregola S., Neuveglise C., Fairhead C., Marck C., Cruz J.A.,
RA   Straub M.L., Kugler V., Sacerdot C., Uzunov Z., Thierry A., Weiss S.,
RA   Bleykasten C., De Montigny J., Jacques N., Jung P., Lemaire M., Mallet S.,
RA   Morel G., Richard G.F., Sarkar A., Savel G., Schacherer J., Seret M.L.,
RA   Talla E., Samson G., Jubin C., Poulain J., Vacherie B., Barbe V.,
RA   Pelletier E., Sherman D.J., Westhof E., Weissenbach J., Baret P.V.,
RA   Wincker P., Gaillardin C., Dujon B., Souciet J.L.;
RT   "Pichia sorbitophila, an interspecies yeast hybrid reveals early steps of
RT   genome resolution following polyploidization.";
RL   G3 (Bethesda) 2:299-311(2012).
CC   -!- FUNCTION: May play a role in ribosome biogenesis.
CC       {ECO:0000256|PIRNR:PIRNR017302}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000256|PIRNR:PIRNR017302}. Nucleus, nucleoplasm
CC       {ECO:0000256|PIRNR:PIRNR017302}.
CC   -!- SIMILARITY: Belongs to the NOP53 family.
CC       {ECO:0000256|ARBA:ARBA00008838, ECO:0000256|PIRNR:PIRNR017302}.
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DR   EMBL; CP002498; AET38144.1; -; Genomic_DNA.
DR   RefSeq; XP_003644961.1; XM_003644913.1.
DR   AlphaFoldDB; G8JP86; -.
DR   STRING; 931890.G8JP86; -.
DR   GeneID; 11471867; -.
DR   KEGG; erc:Ecym_2412; -.
DR   eggNOG; KOG2823; Eukaryota.
DR   HOGENOM; CLU_035888_1_1_1; -.
DR   InParanoid; G8JP86; -.
DR   OMA; TEKWTHK; -.
DR   OrthoDB; 2912665at2759; -.
DR   Proteomes; UP000006790; Chromosome 2.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR   InterPro; IPR011687; Nop53/GLTSCR2.
DR   PANTHER; PTHR14211; GLIOMA SUPPRESSOR CANDIDATE REGION GENE 2; 1.
DR   PANTHER; PTHR14211:SF7; RIBOSOME BIOGENESIS PROTEIN NOP53; 1.
DR   Pfam; PF07767; Nop53; 1.
DR   PIRSF; PIRSF017302; Gltscr2; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR017302};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006790};
KW   Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517,
KW   ECO:0000256|PIRNR:PIRNR017302}.
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          169..188
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          258..317
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          350..371
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        263..283
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   440 AA;  50048 MW;  70F9406FCABFC9B6 CRC64;
     MVANDRPSQY KQSSRKGKKA WRKNIDLTDI ETSIKTSTEH EITHGSSNIT ELPSAALFQV
     DVKGDEALKS KLIKRKQIAK TVKSAEILAA IKDASKVPAL CHPKSSGKKH AKIQGVSKKE
     VSRLMALAGR GLGESKSKAQ VSKEGLIKSK GFDLWGKDNN EVKLPSGIKL NSANGKIPEP
     LLEKSSTGWS VATVAPDTIK RAPVNVKEIN DMPHAGKSYN PDQEHWEQLI KAEYEVEKVN
     ENRRVQLEEY KRKIKHLMET LDDNEEESDE EDESEPENTV SDDEEVGDNV KLSVNAAVKN
     KKKTKYQRNK QKRHEEKVKL QQELKRLKVQ LHQLEKFEDI EIEATKQVQK QVQTGSKTSR
     KVSKNPKLGT KHCVKDNQLE VKFSDELSDS LRKLRPEGNL LYDNMRKLQG SGKIETRVPV
     RKGRKYKKKI TEKWRYKDFK
//